Recombinant Rabbit monoclonal primary
ATG9A Recombinant Rabbit Monoclonal Antibody [SC67-05] (ET1610-71)
Synthetic peptide within c-terminal human atg9a.
HepG2 cell lysates, Hela, 293, rat brain tissue, mouse brain tissue, mouse heart tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
APG9 autophagy 9-like 1 antibody; APG9 like 1 antibody; APG9-like 1 antibody; APG9L1 antibody; ATG9 antibody; ATG9 autophagy related 9 homolog A antibody; ATG9 autophagy related 9 homolog A (S. cerevisiae) antibody; ATG9A antibody; ATG9A_HUMAN antibody; Autophagy 9-like 1 protein antibody; Autophagy related protein 9A antibody; Autophagy-related protein 9A antibody; mATG9 antibody; MGD3208 antibody; OTTHUMP00000206046 antibody; OTTHUMP00000206048 antibody; OTTHUMP00000206049 antibody; OTTHUMP00000206062 antibody
Belongs to the ATG9 family.
Cytoplasmic vesicle, Golgi apparatus, Late endosome membrane, Endoplasmic reticulum membrane.
Autophagy, a process that results in the lysosomal-dependent degradation of cytosolic compartments, is carried out by the autophagosome, which is a double-membrane vesicle whose formation is catalyzed by several autophagy-related gene (Atg) proteins. Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.