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ATBF1 Rabbit Polyclonal Antibody (HA500181)

Price: Regular price $315.00

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Catalog# HA500181

Rabbit Polyclonal to ATBF1

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

ATBF1 Rabbit Polyclonal Antibody (HA500181)

Immunogen

Recombinant protein within human atbf1 aa 1,800-2,000.

Host

Rabbit

Positive Control

Rat esophagus tissue, human colon tissue, human breast carcinoma tissue, human stomach carcinoma tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071278

APPLICATION DILUTION

  • WB

  • 1:5,000 for recombinant protein

  • 1:500 for endogenous lysates (predicted)

  • IHC-P

  • 1:100-1:500

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

404/306 kDa

Isotype

IgG

TARGET

UNIPROT #

Q15911

PROTEIN NAME

ATBF1

SYNONYMS

Zinc finger homeobox protein 3;AT motif-binding factor 1;AT-binding transcription factor 1;Alpha-fetoprotein enhancer-binding protein;Zinc finger homeodomain protein 3;ZFH-3;ZFHX3;ATBF1;C16orf47

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.

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