Mouse monoclonal primary
ASS1 Mouse Monoclonal Antibody [11F1] (EM1701-87)
Recombinant protein within human ass1 aa 1-250.
HepG2, MCF-7, SiHa, human colon cancer tissue, mouse testis tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Argininosuccinate synthase 1 antibody; Argininosuccinate synthase antibody; Argininosuccinate synthetase 1 antibody; ASS antibody; Ass-1 antibody; ass1 antibody; ASSA antibody; ASSY_HUMAN antibody; Citrulline aspartate ligase antibody; Citrulline--aspartate ligase antibody; CTLN1 antibody
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Expressed in adult liver.
Expressed in fetal liver and kidney.
Acetylated by CLOCK in a circadian manner which negatively regulates its enzyme activity. Deacetylated by histone deacetylases.
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.