Positive control:
Lane 1: K562 cell lysate
Lane 2: Human skeletal muscle tissue lysate
Applications
-
WB
-
ICC
-
IF
-
IHC-P
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Asparagine synthetase Recombinant Rabbit Monoclonal Antibody [SC67-07] (ET1610-50)
Immunogen
Recombinant protein
Host
Rabbit
Positive Control
K562, SW480, Hela, SH-SY-5Y, mouse stomach tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
SC67-07
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
61 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:1,000-1:5,000
-
ICC/IF
-
1:50-1:200
-
IHC-P
-
1:50-1:200
TARGET
UNIPROT #
PROTEIN NAME
Asparagine synthetase
SYNONYMS
asnS antibody; ASNS_HUMAN antibody; ASNSD antibody; Asparagine synthetase [glutamine-hydrolyzing] antibody; Asparagine synthetase antibody; Cell cycle control protein TS11 antibody; Glutamine dependent asparagine synthetase 3 antibody; Glutamine dependent asparagine synthetase antibody; Glutamine hydrolyzing antibody; Glutamine-dependent asparagine synthetase antibody; OTTHUMP00000024510 antibody; OTTHUMP00000204938 antibody; OTTHUMP00000204939 antibody; OTTHUMP00000204940 antibody; OTTHUMP00000204941 antibody; OTTHUMP00000204942 antibody; TS11 antibody; TS11 cell cycle control protein antibody
SUBCELLULAR LOCATION
Cytoplasm.
FUNCTION
Glutamine-hydrolyzing asparagine synthetase is also commonly designated cell cycle control protein TS11. Asparagine synthetase plays an important role in the amino-acid biosynthesis pathway and is also important for L-asparagine biosynthesis. Via the L-glutamine route, it is involved in the synthesis of L-asparaine from L-aspartate. The protein contains one asparagine synthetase domain and one type-2 glutamine amidotransferase domain. The cell-cycle regulated gene encoding for asparagine synthetase, ts11, is necessary for G1 progression.