Rabbit polyclonal primary
ASH2L Rabbit Polyclonal Antibody (R1408-1)
Synthetic peptide within human ash2l aa 575-628.
Hela cell lysates, PC-12 cell lysates, mouse colon tissue, human breast carcinoma tissue, human colon tissue, Siha.
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
ASH 2 antibody; Ash2 (absent small or homeotic) like antibody; Ash2 (absent, small, or homeotic) like (Drosophila) antibody; ASH2 antibody; ASH2 LIKE antibody; ASH2 like protein antibody; ASH2-like protein antibody; Ash2l antibody; ASH2L_HUMAN antibody; ASH2L1 antibody; ASH2L2 antibody; Bre 2 antibody; Bre2 antibody; Discs 2-like antibody; Drosophila absent, small, or homeotic antibody; Drosophila ASH2-like antibody; Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody
Transcriptional regulator . Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters . Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 . May play a role in hematopoiesis (PubMed:12670868). In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B .