AMH Rabbit Polyclonal Antibody (HA500137)
Catalog# HA500137
Rabbit Polyclonal to AMH
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WB
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IHC-P
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FC
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Human
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Mouse
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Rat
Positive control:
Lane 1: 293T cell lysate
Lane 2: A431 cell lysate
Lane 3: HepG2 cell lysate
Lane 4: Hela cell lysate
Lane 5: Mouse testis tissue lysate
Lane 6: Rat testis tissue lysate
Specifications
Product Type
Rabbit polyclonal primary
Product Name
AMH Rabbit Polyclonal Antibody (HA500137)
Immunogen
Recombinant protein within human amh aa 50-230.
Host
Rabbit
Positive Control
293T cell lysate, A431 cell lysate, HepG2 cell lysate, Hela cell lysate, mouse testis tissue lysate, rat testis tissue lysate, 293T, rat testis tissue, Hela.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:1,000-1:5,000
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IHC-P
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1:50-1:200
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FC
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1:50-1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 59 kDa.
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
AMH
SYNONYMS
Anti muellerian hormone antibody;MIF antibody;MIS antibody;Muellerian inhibiting factor antibody;Mullerian inhibiting substance antibody
SUBCELLULAR LOCATION
Secreted.
FUNCTION
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.
CITATIONS
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Tang, X., Dong, H., Fang, Z., Li, J., Yang, Q., Yao, T., & Pan, Z.
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells
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WB
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Mouse
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Citation
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Foxl2 is required for the initiation of the female pathway in a temperature-dependent sex determination system in Trachemys scripta
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IF
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Turtles
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Citation
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