PRODUCT CODE: ET7106-64

ALDH1L1 Recombinant Rabbit Monoclonal Antibody [JU53-54] (ET7106-64)

  • Recombinant

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of ALDH1L1 on mouse liver tissue lysates using anti-ALDH1L1 antibody at 1/500 dilution.
  • Western blot analysis of ALDH1L1 on mouse liver tissue lysates using anti-ALDH1L1 antibody at 1/500 dilution.
  • Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-ALDH1L1 antibody. Counter stained with hematoxylin.
Western blot analysis of ALDH1L1 on mouse liver tissue lysates using anti-ALDH1L1 antibody at 1/500 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

ALDH1L1 Recombinant Rabbit Monoclonal Antibody [JU53-54] (ET7106-64)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

A431, A549, LOVO, human liver tissue, human kidney tissue, mouse liver tissue, rat kidney tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JU53-54

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

99 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-2,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

ALDH1L1

SYNONYMS

10 formyltetrahydrofolate dehydrogenase antibody; 10 FTHFDH antibody; 10-formyltetrahydrofolate dehydrogenase antibody; 10-FTHFDH antibody; AL1L1_HUMAN antibody; Aldehyde dehydrogenase 1 family member L1 antibody; Aldehyde dehydrogenase family 1 member L1 antibody; aldh1l1 antibody; Cytosolic 10-formyltetrahydrofolate dehydrogenase antibody; DKFZp781N0997 antibody; EC 1.5.1.6 antibody; FDH antibody; formyltetrahydrofolate dehydrogenase antibody; FTHFD antibody; OTTHUMP00000155221 antibody; OTTHUMP00000214696 antibody; OTTHUMP00000214700 antibody; OTTHUMP00000222724 antibody

SEQUENCE SIMILARITIES

In the N-terminal section; belongs to the GART family.; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.

TISSUE SPECIFICITY

Highly expressed in liver, pancreas and kidney.

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.