Lane 1: Jurkat
Lane 2: A549
Recombinant Rabbit monoclonal primary
AKAP14 Recombinant Rabbit Monoclonal Antibody [SC0667] (ET1610-75)
HUVEC, Jurkat, Hela, A549.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
A kinase (PRKA) anchor protein 14 antibody; A kinase anchor protein 14 antibody; A kinase anchor protein 28 kDa antibody; A-kinase anchoring protein 28 antibody; AKAP14 antibody; AKAP28 antibody; PRKA14 antibody; Protein kinase A anchoring protein 14 antibody
Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Binds to type II regulatory subunits of protein kinase A and anchors/targets them.