AK6 Mouse Monoclonal Antibody [B1-F4] (M1509-2)

UNIPROT #

Q9Y3D8

PROTEIN NAME

AK6

SYNONYMS

AD-004 antibody;Adenylate kinase isoenzyme 6 antibody;Adrenal gland protein AD-004 antibody;AK/ATPase antibody;AK6 antibody;CGI-137 antibody;CIP antibody;Coilin-interacting nuclear ATPase protein antibody;Dual activity adenylate kinase/ATPase antibody;hCINAP antibody;KAD6_HUMAN antibody;TAF9 antibody

SEQUENCE SIMILARITIES

Belongs to the adenylate kinase family. AK6 subfamily.

TISSUE SPECIFICITY

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

In eukaryotic systems, the process of initiating transcription from protein-coding genes requires the presence of RNA polymerase II and a broad family of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that mediate the transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH, and sequence-specific factors that regulate gene expression. TFIID, one of the basal transcription factors, facilitates the preinitiation complex assembly through direct interactions with the TATA promoter element. TAF9 (transcription initiation factor TFIID subunit 9), also known as TAF9A or TAF II p32, is a 264 amino acid nuclear protein that, is a component of the TFIID complex and is required for cell viability.