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Adipose Triglyceride Lipase Rabbit Polyclonal Antibody (HA500301)

Price: Regular price $315.00

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Catalog# HA500301

Rabbit Polyclonal to Adipose Triglyceride Lipase

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

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COA DOWNLOAD

Specifications

Product Type

Rabbit polyclonal primary

Product Name

Adipose Triglyceride Lipase Rabbit Polyclonal Antibody (HA500301)

Immunogen

Synthetic peptide within human adipose triglyceride lipase aa 450-504 / 504 (lumenal).

Host

Rabbit

Positive Control

293 cell lysate, HepG2 cell lysate, A431 cell lysate, human pancreas tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071396

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IHC-P

  • 1:100-1:500

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

55 kDa

Isotype

IgG

TARGET

UNIPROT #

Q96AD5

PROTEIN NAME

Adipose Triglyceride Lipase

SYNONYMS

1110001C14Rik antibody;Adipose triglyceride lipase antibody;ATGL antibody;ATGL DESNUTRIN antibody;Calcium independent phospholipase A2 antibody;Calcium-independent phospholipase A2 antibody;Desnutrin antibody;EC 3.1.1.3 antibody;FP17548 antibody;IPLA2 zeta antibody;IPLA2-zeta antibody;Mutant patatin like phospholipase domain containing 2 antibody;Patatin like phospholipase domain containing 2 antibody;PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2 antibody;Patatin-like phospholipase domain-containing protein 2 antibody;PEDF R antibody;PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA antibody;Pigment epithelium derived factor antibody;Pigment epithelium-derived factor antibody;plpl antibody;plpl2 antibody;PLPL2_HUMAN antibody;Pnpla2 antibody;Transport secretion protein 2 antibody;Transport secretion protein 2.2 antibody;Transport-secretion protein 2 antibody;Triglyceride hydrolase antibody;TTS 2.2 antibody;TTS2 antibody;TTS2.2 antibody;ZETA antibody

SUBCELLULAR LOCATION

Cell membrane, Lipid droplet.

FUNCTION

This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone. Also has acylglycerol transacylase activity. Acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

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