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ACTL6A Recombinant Rabbit Monoclonal Antibody [JU40-32] (ET7106-60)

Price: Regular price $385.00

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Catalog# ET7106-60

Rabbit Monoclonal to ACTL6A

Tested for

  • WB

  • IF-Cell

  • IF-Tissue

  • IHC-P

  • IP

React with

  • Human

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

ACTL6A Recombinant Rabbit Monoclonal Antibody [JU40-32] (ET7106-60)

Immunogen

Recombinant protein within human actl6a aa 185-326 .

Host

Rabbit

Positive Control

Jurkat, mouse brain tissue, LOVO, PC-3M, human tonsil tissue, human spleen tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JU40-32

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IF-Cell

  • 1:50-1:100

  • IF-Tissue

  • 1:50-1:100

  • IHC-P

  • 1:50-1:100

  • IP

  • 1:10-1:50

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

47 kDa

Isotype

IgG

TARGET

UNIPROT #

O96019

PROTEIN NAME

ACTL6A

SYNONYMS

53 kDa BRG1 associated factor A antibody;53 kDa BRG1-associated factor A antibody;ACL6A_HUMAN antibody;Actin like 6A antibody;Actin like protein 6A antibody;Actin related protein 4 antibody;Actin related protein antibody;Actin related protein Baf53a antibody;Actin-like protein 6A antibody;Actin-related protein Baf53a antibody;ACTL 6 antibody;ACTL 6A antibody;ACTL6 antibody;ACTL6A antibody;Arp4 antibody;ARPN BETA antibody;ArpNbeta antibody;BAF 53A antibody;BAF complex 53 kDa subunit antibody;BAF53 antibody;BAF53A antibody;BRG1 associated factor antibody;BRG1-associated factor 53A antibody;hArpN beta antibody;INO80 complex subunit K antibody;INO80K antibody;MGC5382 antibody

SEQUENCE SIMILARITIES

Belongs to the actin family.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.

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