ABCD1 / ALD Recombinant Rabbit Monoclonal Antibody [JE75-07] (HA722413)

UNIPROT #

P33897

PROTEIN NAME

ABCD1 / ALD

SYNONYMS

ABC42 antibody;Abcd1 antibody;ABCD1_HUMAN antibody;Adrenoleukodystrophy protein antibody;ALD antibody;Aldgh antibody;ALDP antibody;AMN antibody;ATP binding cassette, sub family D (ALD), member 1 antibody;ATP-binding cassette sub-family D member 1 antibody;OTTHUMP00000025960 antibody;OTTMUSP00000019283 antibody;RGD1562128 antibody;RP23 373N8.2 antibody;X linked adrenoleukodystrophy (ALD) gene homolog antibody

SUBCELLULAR LOCATION

Peroxisome membrane, Mitochondrion membrane, Lysosome membrane, Endoplasmic reticulum membrane.

FUNCTION

ABCD1 is a protein that transfers fatty acids into peroxisomes. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids.