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IL-31 Mouse Monoclonal Antibody [B7-B0] (M1305-3)

Price: Regular price $350.00

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Catalog# M1305-3

Mouse Monoclonal to IL-31

Tested for

  • WB

  • ELISA

Reacts with

  • Human

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Specifications

Product Type

Mouse monoclonal primary

Product Name

IL-31 Mouse Monoclonal Antibody [B7-B0] (M1305-3)

Immunogen

Recombinant protein within human interleukin 31 aa 1-164 / 164.

Host

Mouse

Positive Control

Bioactive recombinant human IL-31 protein.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

B7-B0

RRID

AB_3073059

APPLICATION DILUTION

  • WB

  • 1:2,000

  • ELISA

  • 1:5,000-1:10,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 18 kDa

Isotype

IgG2a

TARGET

UNIPROT #

Q6EBC2

PROTEIN NAME

IL-31

SYNONYMS

IL 31 antibody;IL-31 antibody;IL31 antibody;IL31_HUMAN antibody;Interleukin 31 antibody;Interleukin-31 antibody

TISSUE SPECIFICITY

Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.

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