Skip to content

Contact

(857) 353-6600

orders@huabio.com

LIMK2 Recombinant Rabbit Monoclonal Antibody [PSH08-82] (HA723034)

Price: Regular price $385.00

Unit price per 

Product size

Bulk Order Quote   |   Customization Request

Catalog# HA723034

Rabbit Monoclonal to LIMK2

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • IP

Reacts with

  • Human

  • Mouse

  • Rat

  • Monkey

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

LIMK2 Recombinant Rabbit Monoclonal Antibody [PSH08-82] (HA723034)

Immunogen

Recombinant protein within human limk2 aa 1-320.

Host

Rabbit

Positive Control

Ramos cell lysate, Jurkat cell lysate, HeLa cell lysate, SW480 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, F9 cell lysate, PC-12 cell lysate, Ranos, PC-12, human colon tissue, human colon cancer tissue, human pancreas tissue, mouse colon tissue, mouse pancreas tissue, rat colon tissue, rat pancreas tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH08-82

APPLICATION DILUTION

  • WB

  • 1:2,000

  • IF-Cell

  • 1:50

  • IHC-P

  • 1:1,000

  • IP

  • 1-2μg/sample

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 72 kDa

Isotype

IgG

TARGET

UNIPROT #

P53671

PROTEIN NAME

LIMK2

SYNONYMS

LIM domain kinase 2 antibody;LIM kinase 2 antibody;LIMK 2 antibody;LIMK-2 antibody;Limk2 antibody;LIMK2_HUMAN antibody

SUBCELLULAR LOCATION

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

FUNCTION

LIM domain kinase 2 is an enzyme that in humans is encoded by the LIMK2 gene. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now