MEK6 Recombinant Rabbit Monoclonal Antibody [PSH07-86] (HA722917)

UNIPROT #

P52564

PROTEIN NAME

MEK6

SYNONYMS

Dual specificity mitogen activated protein kinase kinase 6 antibody;Dual specificity mitogen-activated protein kinase kinase 6 antibody;MAP kinase kinase 6 antibody;MAP2K6 antibody;MAPK/ERK kinase 6 antibody;MAPKK 6 antibody;MAPKK6 antibody;MEK 6 antibody;MEK6 antibody;Mitogen Activated Protein Kinase Kinase 6 antibody;MKK 6 antibody;MKK6 antibody;MP2K6_HUMAN antibody;PRKMK6 antibody;protein kinase antibody;Protein kinase mitogen activated kinase 6 antibody;protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) antibody;SAPK kinase 3 antibody;SAPKK-3 antibody;SAPKK3 antibody;SKK3 antibody;Stress-activated protein kinase kinase 3 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, cytoskeleton.

FUNCTION

Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis.