Dynamin 3 Recombinant Rabbit Monoclonal Antibody [JE54-86]
Catalog# HA722870
Dynamin 3 Recombinant Rabbit Monoclonal Antibody [JE54-86]
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WB
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Human
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Mouse
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unconjugated
Overview
Product Name
Dynamin 3 Recombinant Rabbit Monoclonal Antibody [JE54-86]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Synthetic peptide within Human Dynamin 3 aa 750-850.
Species Reactivity
Human, Mouse
Validated Applications
WB
Target Molecular Weight
Predicted band size: 98 kDa
Positive Control
Human brain tissue lysate, Mouse brain tissue lysate.
Conjugation
unconjugated
Clone Number
JE54-86
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
WB
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1:1,000
Target
Function
Dynamin-3 is a protein that in humans is encoded by the DNM3 gene. The protein encoded by this gene is a member of the dynamin family which possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding. DNM3 is upregulated in Sézary's syndrome.
Background References
1. Lu Q et al. Dynamin 3 Inhibits the Proliferation of Non-small-Cell Lung Cancer Cells by Suppressing c-MET-GBR2-STAT3 Complex Formation. Front Cell Dev Biol. 2021 Aug
2. Cheng SA et al. Expression of DNM3 is associated with good outcome in colorectal cancer. Open Med (Wars). 2022 Jan
Subcellular Location
Cytoplasm, cytoskeleton.
Synonyms
testicular dynamin antibody
testicular antibody
DNM 3 antibody
DNM3 antibody
DNM3 protein antibody
Dyn3 antibody
DYN3_HUMAN antibody
Dyna III antibody
DynaIII antibody
dynamin 2 antibody
ExpandImages
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Western blot analysis of Dynamin 3 on different lysates with Rabbit anti-Dynamin 3 antibody (HA722870) at 1/1,000 dilution.
Lane 1: Human brain tissue lysate
Lane 2: Mouse brain tissue lysate
Lysates/proteins at 40 µg/Lane.
Predicted band size: 98 kDa
Observed band size: 100 kDa
Exposure time: 1 minute; ECL: K1801;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA722870) at 1/1,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Products with the same target and pathway
Dynamin 3 Rabbit Polyclonal Antibody
Application: WB,IF-Cell
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
