PKC zeta Recombinant Rabbit Monoclonal Antibody [PSH06-74] (HA722773)

UNIPROT #

Q05513

PROTEIN NAME

PKC zeta

SYNONYMS

14-3-3-zetaisoform antibody;AI098070 antibody;aPKCzeta antibody;C80388 antibody;EC 2.7.11.13 antibody;KPCZ_HUMAN antibody;nPKC zeta antibody;nPKC-zeta antibody;OTTHUMP00000001368 antibody;OTTHUMP00000044160 antibody;PKC 2 antibody;PKC ZETA antibody;PKC2 antibody;Pkcz antibody;PKCZETA antibody;PKM-zeta, included antibody;PRKCZ antibody;Protein kinase C zeta antibody;Protein kinase C zeta form antibody;Protein kinase C zeta type antibody;r14-3-3 antibody;R74924 antibody;zetaPKC antibody

SUBCELLULAR LOCATION

Cytoplasm, Endosome, Cell junction, Membrane.

FUNCTION

Protein kinase C, zeta (PKCζ), also known as PRKCZ, is a protein in humans that is encoded by the PRKCZ gene. The PRKCZ gene encodes at least two alternative transcripts, the full-length PKCζ and an N-terminal truncated form PKMζ. PKMζ is thought to be responsible for maintaining long-term memories in the brain. Atypical PKC (aPKC) isoforms [zeta (this enzyme) and lambda/iota] play important roles in insulin-stimulated glucose transport. Human adipocytes contain PKC-zeta, rather than PKC-lambda/iota, as their major aPKC. Inhibition of the PKCζ enzyme inhibits insulin-stimulated glucose transport while activation of PKCζ increases glucose transport.