ACADVL / VLCAD Recombinant Rabbit Monoclonal Antibody [JE77-50] (HA722416)

UNIPROT #

P49748

PROTEIN NAME

ACADVL / VLCAD

SYNONYMS

ACAD 6 antibody;ACAD6 antibody;ACADV_HUMAN antibody;Acadvl antibody;Acyl CoA dehydrogenase very long chain antibody;Acyl Coenzyme A dehydrogenase very long chain antibody;LCACD antibody;mitochondrial antibody;Very long chain specific acyl CoA dehydrogenase antibody;Very long chain specific acyl CoA dehydrogenase mitochondrial antibody;Very long-chain specific acyl-CoA dehydrogenase antibody;VLCAD antibody

SUBCELLULAR LOCATION

Mitochondrion inner membrane.

FUNCTION

Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains. Predominantly expressed in heart and skeletal muscle (at protein level). Also detected in kidney and liver (at protein level).