Integrin alpha 9 Recombinant Rabbit Monoclonal Antibody [JE41-58]
Catalog# HA722406
Integrin alpha 9 Recombinant Rabbit Monoclonal Antibody [JE41-58]
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WB
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Human
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Mouse
-
Rat
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unconjugated
Overview
Product Name
Integrin alpha 9 Recombinant Rabbit Monoclonal Antibody [JE41-58]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Synthetic peptide within Human Integrin alpha 9 aa 50-150.
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB
Target Molecular Weight
Predicted band size: 114 kDa
Positive Control
HepG2 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, mouse liver tissue lysate, rat liver tissue lysate.
Conjugation
unconjugated
Clone Number
JE41-58
Reactivity Data
| WB | |
|---|---|
| Human |
|
| Mouse |
|
| Rat |
|
Product Features
Form
Liquid
Concentration
1 mg/mL.(The concentration of this product may be batch-dependent)
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
-
WB
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1:1,000
Target
Function
Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for tenascin-C, VCAM1 and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Background References
1. Hou H et al. ITGA9 Inhibits Proliferation and Migration of Dermal Microvascular Endothelial Cells in Psoriasis. Clin Cosmet Investig Dermatol. 2022 Dec
2. Jin S et al. Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis. Cell Rep. 2023 Jun
Subcellular Location
Membrane.
Synonyms
Alpha RLC antibody
Integrin alpha 4 like antibody
Integrin alpha RLC antibody
Integrin alpha-9 antibody
Integrin alpha-RLC antibody
ITA9_HUMAN antibody
ITGA 4L antibody
ITGA 9 antibody
ITGA4L antibody
ITGA9 antibody
ExpandImages
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Western blot analysis of Integrin alpha 9 on different lysates with Rabbit anti-Integrin alpha 9 antibody (HA722406) at 1/1,000 dilution.
Lane 1: HepG2 cell lysate (20 µg/Lane)
Lane 2: A549 cell lysate (20 µg/Lane)
Lane 3: NIH/3T3 cell lysate (20 µg/Lane)
Lane 4: Mouse liver tissue lysate (40 µg/Lane)
Lane 5: Rat liver tissue lysate (40 µg/Lane)
Predicted band size: 114 kDa
Observed band size: 114 kDa
Exposure time: 1 minute; ECL: K1801;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA722406) at 1/1,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"