Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity) . Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis.
Background References
1. Song P. et. al. Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis. J. Neurochem. 126:451-461(2013).
Western blot analysis of SLC44A4 on Hep G2 (Human liver cancer cell) cell lysate with Rabbit anti-SLC44A4 antibody (HA600017) at 1/2,000 dilution.
Lysates/proteins at 20 µg/Lane. Exposure time: 2 minutes; ECL: K1802
Blocking: 5% NFDM/TBST, 1 hour at room temperature Primary antibody: HA600017, 1/2,000 in 5% NFDM/TBST, overnight at 4 ℃ Secondary antibody: Goat anti-Mouse IgG-HRP (HA1006), 1/50,000 in 5% NFDM/TBST, 1 hour at room temperature
Predicted band size: 79 kDa
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"