GAPDH Mouse Monoclonal Antibody [5-E10] (EM1101)
Catalog# EM1101
Mouse Monoclonal to GAPDH
-
WB
-
IF-Cell
-
IHC-P
-
Human
-
Mouse
-
Rat
-
Zebrafish
-
Rabbit
Lane 1: MDA-MB-231 cell lysate (20 µg/Lane)
Lane 2: HeLa cell lysate (20 µg/Lane)
Lane 3: MCF7 cell lysate (20 µg/Lane)
Lane 4: SK-Br-3 cell lysate (20 µg/Lane)
Lane 5: JAR cell lysate (20 µg/Lane)
Lane 6: NIH/3T3 cell lysate (20 µg/Lane)
Lane 7: C2C12 cell lysate (20 µg/Lane)
Lane 8: PC-12 cell lysate (20 µg/Lane)
Lane 9: Mouse kidney tissue lysate (40 µg/Lane)
Lane 10: Rat liver tissue lysate (40 µg/Lane)
Predicted band size: 36 kDa
Observed band size: 36 kDa
Exposure time: 1 minute 30 seconds;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (EM1101) at 1/5,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody (HA1006) at 1/50,000 dilution was used for 1 hour at room temperature.
Specifications
Product Type
Mouse monoclonal primary
Product Name
GAPDH Mouse Monoclonal Antibody [5-E10] (EM1101)
Immunogen
Synthetic peptide within human gapdh aa 10-50.
Host
Mouse
Positive Control
MDA-MB-231 cell lysate, HeLa cell lysate, MCF7 cell lysate, SK-Br-3 cell lysate, JAR cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, PC-12 cell lysate, mouse kidney tissue lysate, rat liver tissue lysate, F9, Hela, HepG2.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
5-E10
RRID
APPLICATION DILUTION
-
WB
-
1:5,000-1:10,000
-
IF-Cell
-
1:200-1:500
-
IHC-P:1:200-1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2ug/ul
Purification
Protein L affinity purified.
Molecular Weight
Predicted band size: 36 kDa
Isotype
IgM
TARGET
UNIPROT #
PROTEIN NAME
GAPDH
SYNONYMS
38 kDa BFA-dependent ADP-ribosylation substrate antibody;aging associated gene 9 protein antibody;Aging-associated gene 9 protein antibody;BARS-38 antibody;cb609 antibody;EC 1.2.1.12 antibody;Epididymis secretory sperm binding protein Li 162eP antibody;G3P_HUMAN antibody;G3PD antibody;G3PDH antibody;GAPD antibody;GAPDH antibody;Glyceraldehyde 3 phosphate dehydrogenase antibody;Glyceraldehyde-3-phosphate dehydrogenase antibody;HEL-S-162eP antibody;KNC-NDS6 antibody;MGC102544 antibody;MGC102546 antibody;MGC103190 antibody;MGC103191 antibody;MGC105239 antibody;MGC127711 antibody;MGC88685 antibody;OCAS, p38 component antibody;OCT1 coactivator in S phase, 38-KD component antibody;peptidyl cysteine S nitrosylase GAPDH antibody;Peptidyl-cysteine S-nitrosylase GAPDH antibody;wu:fb33a10 antibody
SEQUENCE SIMILARITIES
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
POST-TRANSLATIONAL MODIFICATION
S-nitrosylation of Cys-152 leads to interaction with SIAH1, followed by translocation to the nucleus (By similarity). S-nitrosylation of Cys-247 is induced by interferon-gamma and LDL(ox) implicating the iNOS-S100A8/9 transnitrosylase complex and seems to prevent interaction with phosphorylated RPL13A and to interfere with GAIT complex activity.; ISGylated.; Sulfhydration at Cys-152 increases catalytic activity.; Oxidative stress can promote the formation of high molecular weight disulfide-linked GAPDH aggregates, through a process called nucleocytoplasmic coagulation. Such aggregates can be observed in vivo in the affected tissues of patients with Alzheimer disease or alcoholic liver cirrhosis, or in cell cultures during necrosis. Oxidation at Met-46 may play a pivotal role in the formation of these insoluble structures. This modification has been detected in vitro following treatment with free radical donor (+/-)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide. It has been proposed to destabilize nearby residues, increasing the likelihood of secondary oxidative damages, including oxidation of Tyr-45 and Met-105. This cascade of oxidations may augment GAPDH misfolding, leading to intermolecular disulfide cross-linking and aggregation.; Succination of Cys-152 and Cys-247 by the Krebs cycle intermediate fumarate, which leads to S-(2-succinyl)cysteine residues, inhibits glyceraldehyde-3-phosphate dehydrogenase activity. Fumarate concentration as well as succination of cysteine residues in GAPDH is significantly increased in muscle of diabetic mammals. It was proposed that the S-(2-succinyl)cysteine chemical modification may be a useful biomarker of mitochondrial and oxidative stress in diabetes and that succination of GAPDH and other thiol proteins by fumarate may contribute to the metabolic changes underlying the development of diabetes complications.
SUBCELLULAR LOCATION
Cytoplasm
FUNCTION
GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. It participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. GAPDH is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.
CITATIONS
-
Chen, Y., Zhang, W., Bai, X., & Liu, Y.
Targeting the transcriptional activity of STAT3 by a novel fusion protein
-
WB
-
Human
-
Citation
-
-
Tumstatin attenuates the promotion effect of IL-17 secreted by Th17 cells on the stemness maintenance of glioma cells
-
WB
-
Mouse
-
Citation
-
-
Min Liao
Heat Shock Protein Member 8 Is an Attachment Factor for Infectious Bronchitis Virus
-
WB
-
IP
-
CO-IP
-
chicken
-
Citation
-
-
Hongyan Chen
Down-regulation of FoxM1 by thiostrepton or small interfering RNA inhibits proliferation,transformation ability and angiogenesis,and induces apoptosis of nasopharyngeal carcinoma cells
-
WB
-
human
-
Citation
-
-
Disordered Leptin signaling in the retrotrapezoid nucleus is associated with the impaired hypercapnic ventilatory response in obesity
-
WB
-
Mouse
-
Citation
-
-
Zhonghua Ma
The fungal myosin I is essential for Fusarium toxisome formation
-
WB
-
Fungal strains
-
Citation
-
-
Xuewen Gao
FvSet2 regulates fungal growth,pathogenicity,and secondary metabolism in Fusarium verticillioides
-
WB
-
Fusarium verticillioides
-
Citation
-
-
Zhonghua Ma; Yanni Yin
A fungal ABC transporter FgAtm1 regulates iron homeostasis via the transcription factor cascade FgAreA-HapX
-
WB
-
CO-IP
-
F. graminearum wild-type strain PH-1
-
Citation
-
-
Ren, Q., Tao, S., Guo, F., Wang, B., Yang, L., Ma, L., & Fu, P.
Natural flavonol fisetin attenuated hyperuricemic nephropathy via inhibiting IL-6/JAK2/STAT3 and TGF-β/SMAD3 signaling. Phytomedicine : international journal of phytotherapy and phytopharmacology, 87, 153552.
-
WB
-
IHC
-
Mouse
-
Citation
-
-
Yunxia Li
Radix Polygoni Multiflori and Its Main Component Emodin Attenuate Non-Alcoholic Fatty Liver Disease in Zebrafish by Regulation of AMPK Signaling Pathway
-
WB
-
zebrafish
-
Citation
-
-
Tao Xu;Aizhong Wang
Spinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception
-
WB
-
mice
-
Citation
-
-
Yuanxiao Yang;Changyu Li
The Protective Effect of Shen Qi Wan on Adenine-Induced Podocyte Injury
-
WB
-
mice
-
Citation
-
-
Jiyong Zhou
Ubiquitination Is Essential for Avibirnavirus Replication by Supporting VP1 Polymerase Activity
-
WB
-
human
-
Citation
-
-
Wu, H., Yang, H., Ji, G., Zheng, T., Zhang, Y., Deng, T., Zheng, X., Zhou, J., & Hu, B.
SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1. Journal of virology, 93(10), e02227-18.
-
WB
-
Citation
-
-
Xin Zhua
Biochemical changes of salivary gland adenoid cystic carcinoma cells induced by SGI-1776
-
WB
-
human
-
Citation
-
-
Boli Hu;Jiyong Zhou
Influenza A Virus Induces Autophagy by Its Hemagglutinin Binding to Cell Surface Heat Shock Protein 90AA1
-
WB
-
CoIP
-
Chicken
-
Citation
-
-
Wang, X., Li, M., Zhang, X., Li, Y., He, G., Dinnyés, A., Sun, Q., & Xu, W.
CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D
-
WB
-
Human
-
Citation
-
-
Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of β-Carbolines as Promising Antifungal and Antibacterial Candidates.
-
Zhang, L., Li, Y., Dong, L., Sun, K., Liu, H., Ma, Z., Yan, L., & Yin, Y.
MAP Kinase FgHog1 and Importin β FgNmd5 Regulate Calcium Homeostasis in Fusarium graminearum
-
WB
-
Citation
-
-
Yanning Liu
Direct targeting sperm-associated antigen 9 by miR-141 influences hepatocellular carcinoma cell growth and metastasis via JNK pathway
-
WB
-
human
-
Citation
-
-
Gu, Q., Wang, Y., Zhao, X., Yuan, B., Zhang, M., Tan, Z., Zhang, X., Chen, Y., Wu, H., Luo, Y., Keller, N. P., Gao, X., & Ma, Z.
Inhibition of histone acetyltransferase GCN5 by a transcription factor FgPacC controls fungal adaption to host-derived iron stress
-
WB
-
Citation
-
-
Unilateral injection of botulinum toxin type A into the masseter muscle induces mandibular asymmetry in adolescent rats by suppressing the angular process growth
-
WB
-
Rat
-
Citation
-
-
Li, T., Wang, H., Xia, K., Wu, Z., Liu, R., Yin, X., Zhou, C., Li, Y., & Zou, S.
Long noncoding RNA expression profiles in intermittent parathyroid hormone induced cementogenesis. Genomics, 113(1 Pt 1), 217–228.
-
WB
-
Mouse
-
Citation
-
-
Pan, G., Zhong, M., Yao, J., Tan, J., Zheng, H., Jiang, Y., Tang, Y., Zhou, H., Qin, D., Yu, X., Liu, L., Li, Z., Lin, Z., Jiang, Y., Xu, B., & Zha, J.
Orelabrutinib and venetoclax synergistically induce cell death in double hit lymphoma by interfering with the crosstalk between the PI3K/AKT and p38/MAPK signaling
-
WB
-
Human
-
Citation
-
-
Chen, W., Xu, Z., You, W., Zhou, Y., Wang, L., Huang, Y., & Shan, T.
Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy
-
WB
-
Mouse
-
Citation
-
-
He, X., Xie, J., Zhang, J., Wang, X., Jia, X., Yin, H., Qiu, Z., Yang, Z., Chen, J., Ji, Z., Yu, W., Chen, M., Xu, W., & Gao, H.
Acid‐Responsive Dual‐Targeted Nanoparticles Encapsulated Aspirin Rescue the Immune Activation and Phenotype in Autism Spectrum Disorder
-
Mouse
-
Citation
-
-
Guanwei Fan,Yi Wang
Analysis of microRNA Expression Profiles Induced by Yiqifumai Injection in Rats with Chronic Heart Failure
-
WB
-
rats
-
Citation
-
-
The transcription factor FgStuA regulates virulence and mycotoxin biosynthesis via recruiting the SAGA complex in Fusarium graminearum
-
Co-IP
-
Citation
-
-
Hu Chen; Zhi-Xiong Jim Xiao
Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis
-
WB
-
human
-
Citation
-
-
Yao, W., Ma, A., Zhang, Z., & Zhu, L.
Intermittent Hydrostatic Pressure Promotes Cartilage Repair in an Inflammatory Environment through Hippo-YAP Signaling In Vitro and In Vivo
-
WB
-
Rat
-
Citation
-
-
Wang, M., Ma, T., Wang, H., Liu, J., Chen, Y., Shim, W. B., & Ma, Z.
The RNA binding protein FgRbp1 regulates specific pre-mRNA splicing via interacting with U2AF23 in Fusarium. Nature communications, 12(1), 2661.
-
WB
-
Fusarium
-
Citation
-
-
Zhu, Y., Wang, Y., Tao, B., Han, J., Chen, H., Zhu, Q., Huang, L., He, Y., Hong, J., Li, Y., Chen, J., Huang, J., Lo, L. J., & Peng, J.
Nucleolar GTPase Bms1 displaces Ttf1 from RFB-sites to balance progression of rDNA transcription and replication
-
WB
-
Zebrafish
-
Citation
-
-
Wenyong Shao
The endocytic cargo adaptor complex is required for cell-wall integrity via interacting with the sensor FgWsc2B in Fusarium graminearum.
-
CO-IP
-
Fusarium graminearum strain
-
Citation
-
-
HapX-mediated H2B deub1 and SreA-mediated H2A.Z deposition coordinate in fungal iron resistance
-
Co-IP
-
WB
-
Citation
-
-
Qingfeng Tang
Characterization of the Expression and Functions of Two Odorant-Binding Proteins of Sitophilus zeamais Motschulsky (Coleoptera: Curculionoidea)
-
WB
-
Sitophilus zeamais Motschulsky
-
Citation
-
-
Xiaojian Wang
Protein Kinase Serine/Threonine Kinase 24 Positively Regulates Interleukin 17-Induced Inflammation by Promoting IKK Complex Activation
-
WB
-
mice
-
Citation
-
-
Zhuo, J., Lu, D., Lin, Z., Yang, X., Yang, M., Wang, J., Tao, Y., Wen, X., Li, H., Lian, Z., Cen, B., Dong, S., Wei, X., Xie, H., Zheng, S., Shen, Y., & Xu, X.
The distinct responsiveness of cytokeratin 19-positive hepatocellular carcinoma to regorafenib
-
WB
-
Citation
-
-
Li, L., Tao, S., Guo, F., Liu, J., Huang, R., Tan, Z., Zeng, X., Ma, L., & Fu, P.
Genetic and pharmacological inhibition of fatty acid-binding protein 4 alleviated inflammation and early fibrosis after toxin induced kidney injury. International immunopharmacology, 96, 107760. Advance online publication.
-
H Chen
Induction and inhibition of the pan-nuclear gamma-H2AX response in resting human peripheral blood lymphocytes after X-ray irradiation
-
WB
-
human
-
Citation
-
-
Huijun Wu,Xuewen Gao
Involvement of FvSet1 in Fumonisin B1 Biosynthesis,Vegetative Growth,Fungal Virulence,and Environmental Stress Responses in Fusarium verticillioides
-
WB
-
Fungal Strains
-
Citation
-
-
Professor Mingjun Xie
Prognostic and predictive value of monocarboxylate transporter 4 in patients with breast cancer
-
IHC
-
WB
-
human
-
Citation
-
-
Xu G
Transcription factor IKZF1 is degraded during the apoptosis of multiple myeloma cells induced by kinase inhibition
-
WB
-
human
-
Citation
-
-
Chen, A., Ren, Y., Han, X., Liu, C., Zhou, Y., Xu, C., Qi, H., Ma, Z., & Chen, Y.
The COP9 signalosome complex regulates fungal development and virulence in the wheat scab fungus Fusarium graminearum
-
WB
-
Citation
-
-
Dahai Hu
Curcumin pretreatment protects against hypoxia/reoxgenation injury via improvement of mitochondrial function,destabilization of HIF-1α and activation of Epac1-Akt pathway in rat bone marrow mesenchymal stem cells.
-
WB
-
rat
-
Citation
-
-
Jian, Y., Chen, X., Ahmed, T., Shang, Q., Zhang, S., Ma, Z., & Yin, Y.
Toxicity and action mechanisms of silver nanoparticles against the mycotoxin-producing fungus Fusarium graminearum
-
WB
-
Fusarium graminearum
-
Citation
-
-
Minghua Ge
Expression of PIM-1 in salivary gland adenoid cystic carcinoma: Association with tumor progression and patients' prognosis
-
WB
-
human
-
Citation
-
-
Zhao, Qingqing et al
LASS2 enhances p53 protein stability and nuclear import to suppress liver cancer progression through interaction with MDM2/MDMX
-
WB
-
Human
-
Citation
-
-
Liu, N., Zhu, M., Zhang, Y., Wang, Z., Li, B., & Ren, W.
Involvement of the Autophagy Protein Atg1 in Development and Virulence in Botryosphaeria dothidea
-
WB
-
Citation
-
-
YUN CHEN
Capping proteins regulate fungal development,DON‐toxisome formation and virulence in Fusarium graminearum
-
WB
-
Fusarium graminearum
-
Citation
-
-
Lijuan Chen,Yiguo Hu
Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma
-
WB
-
mouse
-
Citation
-
-
Feng, Y. L., Liu, Q., Chen, R. D., Liu, S. C., Huang, Z. C., Liu, K. M., Yang, X. Y., & Xie, A. Y.
DNA nicks induce mutational signatures associated with BRCA1 deficiency
-
WB
-
Citation
-
-
Lin, Z. H., Liu, Y., Xue, N. J., Zheng, R., Yan, Y. Q., Wang, Z. X., Li, Y. L., Ying, C. Z., Song, Z., Tian, J., Pu, J. L., & Zhang, B. R.
Quercetin Protects against MPP+/MPTP-Induced Dopaminergic Neuron Death in Parkinson's Disease by Inhibiting Ferroptosis
-
WB
-
Human
-
Citation
-
-
Yuancun Liang
Endocytic FgEde1 regulates virulence and autophagy in Fusarium graminearum
-
WB
-
Fusarium graminearum
-
Citation
-
-
Wenchan Chen
The Autophagy Gene BcATG8 Regulates the Vegetative Differentiation and Pathogenicity of Botrytis cinerea
-
WB
-
Botrytis cinerea
-
Citation
-
-
Ming-hua Ge
Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma
-
WB
-
human
-
Citation
-
-
Dong, J., Zhong, T., Xu, Z., Chen, H., Wang, X., Yang, L., Lou, Z., Xu, Y., Hou, T., Xu, R., Zhu, W., & Shao, J.
Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model
-
WB
-
Citation
-
-
Tizhong Shan
GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
-
WB
-
mice
-
Citation
-
-
Huijun Wu
Bacillomycin D Produced by Bacillus amyloliquefaciens Is Involved in the Antagonistic Interaction with the Plant-Pathogenic Fungus Fusarium graminearum
-
WB
-
Bacterial and fungal strains
-
Citation
-
-
Chengwei Liang
Defective autophagy leads to the suppression of stem-like features of CD271+osteosarcoma cells
-
WB
-
human
-
Citation
-
-
Zhang Ming
Aire Promotes the Self-Renewal of Embryonic Stem Cells Through Lin28
-
WB
-
mouse
-
Citation
-
-
Ren, W., Zhang, Y., Zhu, M., Liu, Z., Lian, S., Wang, C., Li, B., & Liu, N.
The Phosphatase Cascade Nem1/Spo7-Pah1 Regulates Fungal Development, Lipid Homeostasis, and Virulence in Botryosphaeria dothidea
-
WB
-
Citation
-
-
Yun Chen
The b-ZIP transcription factor FgTfmI is required for the fungicide phenamacril tolerance and pathogenecity in Fusarium graminearum.
-
WB
-
Fusarium graminearum
-
Citation
-
-
The sorting nexin FgAtg20 is involved in the Cvt pathway, non‐selective macroautophagy, pexophagy and pathogenesis in Fusarium graminearum
-
WB
-
Citation
-
-
Liu, H., Lou, J., Liu, Y., Liu, Z., Xie, J., Sun, J., Pan, H., & Han, W.
Intestinal epithelial cell autophagy deficiency suppresses inflammation-associated colon tumorigenesis
-
WB
-
Mouse
-
Citation
-
-
Tizhong Shan
Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
-
WB
-
mice
-
Citation
-
-
Wang, H., Li, T., Wang, X., Guan, Y., Jiang, Y., Chen, S., Zou, S., & Duan, P.
Mechanisms of sphingosine-1-phosphate (S1P) signaling on excessive stress-induced root resorption during orthodontic molar intrusion
-
WB
-
Rat
-
Citation
-
-
Li, H., Song, D., Liu, Q., Li, L., Sun, X., Guo, J., Li, D., & Li, P.
miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation
-
WB
-
Mouse
-
Citation
-
-
Intrinsic color sensing system allows for real-time observable functional changes on human induced pluripotent stem cell-derived cardiomyocytes
-
WB
-
Human
-
Citation
-
-
Linrong Lu
Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1.
-
WB
-
mouse
-
Citation
-
-
Zhi Chen
Hepatitis B Virus Middle Protein Enhances IL-6 Production via p38 MAPK/NF-κB Pathways in an ER Stress-Dependent Manner
-
WB
-
human
-
Citation
-
-
Yuancun Liang,Jinfeng Yu
FgPEX4 is involved in development,pathogenicity,and cell wall integrity in Fusarium graminearum.
-
WB
-
Fusarium graminearum
-
Citation
-
-
Wang, X., Lin, L., Yu, Y., Yan, Y., Ojha, N. K., & Zhou, J.
The N-terminal residual arginine19 of influenza A virus NS1 protein is required for its nuclear localization and RNA binding. Veterinary microbiology, 251, 108895.
-
Yao, J., Lin, C., Jiang, J., Zhang, X., Li, F., Liu, T., & Diao, H.
lncRNA-HEIM Facilitated Liver Fibrosis by Up-Regulating TGF-β Expression in Long-Term Outcome of Chronic Hepatitis B. Frontiers in immunology, 12, 666370.
-
WB
-
Human
-
Citation
-
-
Shen, Z. J., Fu, Y. B., Hou, J. L., Lin, L. N., Wang, X. Y., Li, C. Y., & Yang, Y. X.
Integrating network pharmacology, UPLC-Q-TOF-MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
-
WB
-
Mouse
-
Citation
-
-
C. Wang
Stage-specific functional relationships between Tub1 and Tub2 beta-tubulins in the wheat scab fungus Fusarium graminearum.
-
WB
-
Fusarium graminearum
-
Citation
-
-
Tang, G., Yuan, J., Wang, J., Zhang, Y. Z., Xie, S. S., Wang, H., Tao, Z., Liu, H., Kistler, H. C., Zhao, Y., Duan, C. G., Liu, W., Ma, Z., & Chen, Y.
Fusarium BP1 is a reader of H3K27 methylation
-
WB
-
Citation
-
-
Baobing Yin
LMO3 promotes hepatocellular carcinoma invasion,metastasis and anoikis inhibition by directly interacting with LATS1 and suppressing Hippo signaling
-
IHC
-
WB
-
human
-
Citation
-
-
Changchun Kang
High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome
-
WB
-
human
-
Citation
-
-
Liu, Q., Guo, L., Qi, H., Lou, M., Wang, R., Hai, B., Xu, K., Zhu, L., Ding, Y., Li, C., Xie, L., Shen, J., Xiang, X., & Shao, J.
A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer. Cell death & disease, 12(7), 683.
-
WB
-
Mouse
-
Citation
-
-
Jia-Sheng Wu;Zheng-Tao Wang;Yue-Ming Ma
Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats.
-
WB
-
rat
-
Citation
-
-
Yanning Liu & Min Zheng
0404 inhibits hepatocellular carcinoma through a p53/miR-34a/ SIRT1 positive feedback loop
-
WB
-
human
-
Citation
-
-
Lu Hong
Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model
-
None
-
rat
-
Citation
-
-
Jiang, X., Zhang, Y., Zhang, H., Zhang, X., Yin, X., Yuan, F., Wang, S., & Tian, Y.
Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43
-
WB
-
Rat
-
Citation
-
-
Min Liao
Rabies virus phosphoprotein P5 binding to BECN1 regulates self-replication by BECN1-mediated autophagy signaling pathway. Cell communication and signaling : CCS, 18(1), 153.
-
WB
-
CoIP
-
human
-
Citation
-
-
Zhenyu Ju & Yu-Sheng Cong
A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1a stability
-
WB
-
human
-
Citation
-
-
Samie R. Jaffrey,Guoqiang Xu
A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function
-
WB
-
Human
-
Citation
-
-
Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation
-
WB
-
Nile tilapia
-
Citation
-
-
Hu, X., Xiao, G., He, L., Niu, X., Li, H., Lou, T., Hu, Q., Yang, Y., Xu, Q., Wei, Z., Qiu, M., Tanaka, K. F., Shen, Y., & Tao, Y.
Sustained ErbB Activation Causes Demyelination and Hypomyelination by Driving Necroptosis of Mature Oligodendrocytes and Apoptosis of Oligodendrocyte Precursor Cells
-
WB
-
Mouse
-
Citation
-
-
Lu, X. X., Jiang, Y. Y., Wu, Y. W., Chen, G. Y., Shao, C. L., Gu, Y. C., Liu, M., & Wei, M. Y.
Semi-Synthesis, Cytotoxic Evaluation, and Structure—Activity Relationships of Brefeldin A Derivatives with Antileukemia Activity
-
WB
-
Botrytis cinerea
-
Citation
-
-
Fei Wang
Dietary quercetin potentiates the antiproliferative effect of interferon-α in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase
-
WB
-
human
-
Citation
-
-
Dr Shengmei Zhu
miR-29a ameliorates ischemic injury of astrocytes in vitro by targeting the water channel protein aquaporin 4
-
WB
-
mice
-
Citation
-
-
Zhonghua Ma & Yanni Yin
A phosphorylated transcription factor regulates sterol biosynthesis in Fusarium graminearum
-
CO-IP
-
Fusarium graminearum
-
Citation
-
-
Qing Xu,Zhigang Zhang
Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling
-
WB
-
mice
-
Citation
-
-
GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1
-
WB
-
Mouse
-
Citation
-
-
Muhammad A
iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains
-
WB
-
Bombyx mori
-
Citation
-
-
Shenshen Zou;Yuancun Liang
Mitochondrial FgEch1 is responsible for conidiation and full virulence in Fusarium graminearum
-
WB
-
Fusarium graminearum
-
Citation
-
Newsletter
Just like the interactions between antigens and antibodies, the higher the affinity between you and us the better.
Popup
Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.
Age verification
By clicking enter you are verifying that you are old enough to consume alcohol.