Lane 1: SH-SY-5Y
Lane 2: 293T
Recombinant Rabbit monoclonal primary
14-3-3 epsilon Recombinant Rabbit Monoclonal Antibody [JJ08-40] (ET1701-1)
SH-SY-5Y, NIH/3T3, Hela, 293T, human colon cancer tissue, mouse placenta tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
14 3 3 E antibody; 14 3 3 epsilon antibody; 14 3 3E antibody; 14-3-3 protein epsilon antibody; 14-3-3E antibody; 1433E_HUMAN antibody; Epididymis luminal protein 2 antibody; FLJ45465 antibody; FLJ53559 antibody; HEL2 antibody; KCIP 1 antibody; KCIP1 antibody; MDCR antibody; MDS antibody; Mitochondrial import stimulation factor L subunit antibody; Protein kinase C inhibitor protein1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon polypeptide antibody; Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide antibody; YWHAE antibody
Belongs to the 14-3-3 family.
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.