Lane 1: Hela cell lysate
Lane 2: A431 cell lysate
Recombinant Rabbit monoclonal primary
RPS20 Recombinant Rabbit Monoclonal Antibody [SC65-08] (ET1610-83)
Synthetic peptide within human rps20 aa 36-80 / 119.
A431, Hela, B16-F1.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
40S ribosomal protein S20 antibody; Ribosomal protein S20 antibody; RPS 20 antibody; RpS20 antibody; RS20_HUMAN antibody; S20 antibody
Belongs to the universal ribosomal protein uS10 family.
Monoubiquitinated by ZNF598 when a ribosome has stalled during translation of poly(A) sequences, leading to preclude synthesis of a long poly-lysine tail and initiate the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide.
Mammalian ribosomal proteins are encoded by multigene families that consist of processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S20, also known as RPS20, is a 119 amino acid cytoplasmic protein that is a component of the 40S ribosomal subunit. Co-transcribed with the small nucleolar RNA gene U54, Ribosomal Protein S20 is a primary binding protein (it binds independently to its target protein) that interacts with both the 5’ and 3’ minor domains of 16S ribosomal RNA (rRNA). Through its interactions with 16S rRNA, Ribosomal Protein S20 is thought to play a key role in nucleating the assembly of the 30S ribosomal subunit. Like most ribosomal protein-coding genes, the gene encoding Ribosomal Protein S20 is dispersed throughout the genome and exists as multiple processed pseudogenes.
Wang, M., Ma, T., Wang, ......
Wang, M., Ma, T., Wang, H., Liu, J., Chen, Y., Shim, W. B., & Ma, Z. (2021). The RNA binding protein FgRbp1 regulates specific pre-mRNA splicing via interacting with U2AF23 in Fusarium. Nature communications, 12(1), 2661.