NLRP3 Recombinant Rabbit Monoclonal Antibody [SC06-23] (ET1610-93)

Lao, A., Wu, J., Li, D., Shen, A., Li, Y., Zhuang, Y., Lin, K., Wu, J., & Liu, J.

Functionalized Metal-Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

Liu Li,et al

Ghrelin suppresses hypoxia/reoxygenation-induced H9C2 cell pyroptosis via NLRP3

IL‐1β promotes IL‐17A production of ILC3s to aggravate neutrophilic airway inflammation in mice

Wang Yue,et al

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway

Shah W, Zhao Q, Wang S, et al

Polydatin improves vascular endothelial function by maintaining mitochondrial homeostasis under high glucose conditions

Zheng, X., Gong, T., Tang, C., Zhong, Y., Shi, L., Fang, X., Chen, D., & Zhu, Z.

Gastrodin improves neuroinflammation-induced cognitive dysfunction in rats by regulating NLRP3 inflammasome

Li Jing,et al

Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights

Wang, H., Huang, M., Wang, W., Zhang, Y., Ma, X., Luo, L., Xu, X., Xu, L., Shi, H., Xu, Y., Wang, A., & Xu, T.

Microglial TLR4-induced TAK1 phosphorylation and NLRP3 activation mediates neuroinflammation and contributes to chronic morphine-induced antinociceptive tolerance

Oral Delivery of Mouse β-Defensin 14 (mBD14)-Producing Lactococcus lactis NZ9000 Attenuates Experimental Colitis in Mice

Guo Zhuling,et al

Regulation of the AGEs-induced inflammatory response in human periodontal ligament cells via the AMPK/NF-κB/NLRP3 signaling pathway

Lai Yingying,et al

Dihydrocapsaicin suppresses the STING-mediated accumulation of ROS and NLRP3 inflammasome and alleviates apoptosis after ischemia-reperfusion injury of perforator skin flap

Wang, Y., Sun, Z., Zhang, H., Song, Y., Wang, Y., Xu, W., & Li, M.

CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages

Formononetin alleviates acute pancreatitis by reducing oxidative stress and modulating intestinal barrier

Qing-quan Zeng,et al

Gelsevirine ameliorates sepsis-associated encephalopathy by inhibiting the STING signalling-mediated pyroptosis pathway in microglia

Ginsenoside Rh2 Inhibits NLRP3 Inflammasome Activation and Improves Exosomes to Alleviate Hypoxia-Induced Myocardial Injury

Yi X, Song Y, Xu J, et al

NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-κB signaling in human periodontal ligament cells

Inhibition of P2X7 Purinergic Receptor Ameliorates Cardiac Fibrosis by Suppressing NLRP3/IL-1β Pathway

PD184352 exerts anti-inflammatory and antioxidant effects by promoting activation of the Nrf2/HO-1 axis

Zhang, X., Li, F., Wang, W., Ji, L., Sun, B., Xiao, X., Wang, X., Chen, Y., Liu, B., Ye, W., Tian, C., Wang, H., & Zheng, Y.

Macrophage pyroptosis is mediated by immunoproteasome subunit β5i (LMP7) in abdominal aortic aneurysm

Lai Yingying,et al

Puerarin enhances TFEB-mediated autophagy and attenuates ROS-induced pyroptosis after ischemic injury of random-pattern skin flaps

Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage.

Linxi Lv , Hui Jiang , Dianze Song ,et al

Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression

Lulu Tang , Dongdong Zhang , Yujing Zhang,et al

Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis

Wu Qian,et al

Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis

Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway

Luo Ruixi

Hesperidin Protects Against High-Fat Diet-Induced Lipotoxicity in Rats by Inhibiting Pyroptosis

Dietary Zinc Ameliorates TNBS-Induced Colitis in Mice Associated with Regulation of Th1/Th2/Th17 Balance and NF-κB/NLRP3 Signaling Pathway.

Xiaoman Yuan , Siyi Han , Anne Manyande , et al

Spinal voltage-gated potassium channel Kv1.3 contributes to neuropathic pain via the promotion of microglial M1 polarization and activation of the NLRP3 inflammasome

Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway

HSP60 Regulates Monosodium Urate Crystal-Induced Inflammation by Activating the TLR4-NF-κB-MyD88 Signaling Pathway and Disrupting Mitochondrial Function

Aixin Hu , Wenxia Huang , Xin Shu , Shiyue Ma , Caimei Yang , Ruiqiang Zhang , Xiao Xiao , Yanping Wu

Lactiplantibacillus plantarum Postbiotics Suppress Salmonella Infection via Modulating Bacterial Pathogenicity, Autophagy and Inflammasome in Mice

Yao, M., Wang, Z., Jiang, L., Wang, L., Yang, Y., Wang, Q., Qian, X., Zeng, W., Yang, W., Liang, R., & Qian, J.

Oxytocin ameliorates high glucose- and ischemia/reperfusion-induced myocardial injury by suppressing pyroptosis via AMPK signaling pathway

Kai Zheng,Yifei Wang

AT-533,a Hsp90 inhibitor,attenuates HSV-1-induced inflammation.

Wang Junli,et al

Huanglian Jiedu Decoction Inhibits LPS-induced Neuroinflammation and Attenuates the 
Activation of NLRP3 Inflammasome in 
BV2 Cells

Wu, Y., Hu, A., Shu, X., Huang, W., Zhang, R., Xu, Y., & Yang, C.

Lactobacillus plantarum postbiotics trigger AMPK-dependent autophagy to suppress Salmonella intracellular infection and NLRP3 inflammasome activation

Dingming Huang ; Lan Zhang

The effect of NLRP inflammasome on the regulation of AGEs‐ induced inflammatory response in human periodontal ligament cells

HSP60 regulates the cigarette smoke-induced activation of TLR4-NF-κB-MyD88 signalling pathway and NLRP3 inflammasome

Zou Kaiao,et al

Aucubin Alleviates Intervertebral Disc Degeneration by Repressing NF-κB-NLRP3 Inflammasome Activation in Endplate Chondrocytes

Zhang Xianzheng,et al

Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12

Li, Xin;Wang, Chunchun;Zhu, Jiang;Lin, Qian;Yu, Minjie;Wen, Jiashu;Feng, Jie;Hu, Caihong

Sodium Butyrate Ameliorates Oxidative Stress-Induced Intestinal Epithelium Barrier Injury and Mitochondrial Damage through AMPK-Mitophagy Pathway

Supramolecular salicylic acid ameliorates rosacea-like eruptions by suppressing NLRP3-mediated inflammasome activation in mice

Dehydromevalonolactone ameliorates liver fibrosis and inflammation by repressing activation of NLRP3 inflammasome

Jiang, H., Chen, F., Song, D., Zhou, X., Ren, L., & Zeng, M.

Dynamin-Related Protein 1 Is Involved in Mitochondrial Damage, Defective Mitophagy, and NLRP3 Inflammasome Activation Induced by MSU Crystals

Neuroprotective effects of Jie-du-huo-xue decoction on microglia pyroptosis after cerebral ischemia and reperfusion——From the perspective of glial-vascular unit

Luo Ruixi,et al

Penthorum chinense Pursh extract ameliorates hepatic steatosis by suppressing pyroptosis via the NLRP3/Caspase‐1/GSDMD pathway

Contribution of diabetes mellitus to periodontal inflammation during orthodontic tooth movement

Wei Shi,et al

Copper induced cytosolic escape of mitochondrial DNA and activation of cGAS-STING-NLRP3 pathway-dependent pyroptosis in C8-D1A cells

Cui, B., Liu, Y., Chen, J., Chen, H., Feng, Y., & Zhang, P.

Small molecule inhibitor CRT0066101 inhibits cytokine storm syndrome in a mouse model of lung injury

Liu, Y., Guo, X., Zhang, J., Han, X., Wang, H., Du, F., Zeng, X., & Guo, C.

Protective Effects of the Soluble Receptor for Advanced Glycation End-Products on Pyroptosis during Myocardial Ischemia-Reperfusion

Sevoflurane preconditioning improves neuroinflammation in cerebral ischemia/reperfusion induced rats through ROS-NLRP3 pathway

Voluven treatment could induce NLRP3 inflammasome-mediated pyroptosis of bone marrow-derived macrophages

Fan Yujie,et al

Coordination-Driven Nanomedicine Mitigates One-Lung Ventilation-Induced Lung Injury via Radicals Scavenging and Cell Pyroptosis Inhibition

Wu Xinyi,et al

Oridonin attenuates liver ischemia–reperfusion injury by suppressing PKM2/NLRP3-mediated macrophage pyroptosis

Yu Jingyue,et al

Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation

Xin, Y., Wang, W., Mao, E., Yang, H., & Li, S.

Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis

Tao Xu;Aizhong Wang

Spinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception

Mi Ai,et al

Hepatoprotective efficacy and interventional mechanism of panaxanediol saponins component in high-fat diet-induced NAFLD mice

Ding, L., Liao, T., Yang, N., Wei, Y., Xing, R., Wu, P., Li, X., Mao, J., & Wang, P.

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling