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Mouse IL-33 enzyme-linked immunoassay kit(EM0033)

Price: Regular price $499.00

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Catalog# EM0033

Assay type Sandwich ELISA

Range 6.86~5000 pg/ml

Sensitivity 0.33 pg/ml (10 μl)

Reacts with

  • Mouse

PERFORMANCE CHARACTERISTICS

Sensitivity

0.33 pg/ml (10 μl)

Range

6.86~5000 pg/ml

Recovery

The spike recovery was evaluated by spiking 3 levels of mouse IL-33 into health mouse serum sample. The un-spiked serum was used as blank in this experiment. The recovery ranged from 84% to 107% with an overall mean recovery of 94%.

Specifications

Product Type

ELISA Kit

Product Name

Mouse IL-33 enzyme-linked immunoassay kit(EM0033)

Detection method

Colorimetric

Sample type

Serum

Assay type

Sandwich ELISA

Category

PROPERTIES

Storage instructions

Store at +4℃

Kits Components

Coated Plate

96 well

Standard

9 vial

Detect Antibody

6 ml/bottle

Streptavidin-HRP

12 ml/bottle

Assay Buffer

12 ml/bottle

Stop Solution

12 ml/bottle

Wash Buffer

50 ml/bottle

Sealer Film

6 pieces

TARGET

UNIPROT #

Q8BVZ5

PROTEIN NAME

IL-33

SYNONYMS

Interleukin-33 IL-33 Interleukin-33(102-266) Interleukin-33(109-266) Il33

FUNCTION

IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.

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