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Human CD30/TNFRSF8, C-His, Flag Tag (ECD) Protein (HA210649)

Price: Regular price $159.00

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Catalog# HA210649-20UG

Reacts with

  • Human

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Product Details

Product Type

Protein

Product Name

Human CD30/TNFRSF8, C-His, Flag Tag (ECD) Protein (HA210649)

Predicted molecular mass

41.7 kD

Protein construction description

A DNA sequence encoding the human CD30/TNFRSF8 protein (P28908) (Phe 19-Gly 385) was expressed with both His and Flag tag at the C-terminus.

Accession

P28908

Protein construction

CD30/TNFRSF8 (19-385) | His | Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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