Recombinant Rabbit monoclonal primary
Cytokeratin 10 Recombinant Rabbit Monoclonal Antibody [ST05-43] (ET1609-75)
Synthetic peptide within human cytokeratin 10 aa 541-584 / 584.
Human skin tissue lysates, Hela, human tonsil tissue, mouse skin tissue, rat skin tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
BCIE antibody; BIE antibody; CK 10 antibody; CK-10 antibody; Cytokeratin-10 antibody; EHK antibody; K10 antibody; K1C10_HUMAN antibody; Keratin 10 antibody; Keratin antibody; Keratin type i cytoskeletal 10 antibody; Keratin type I cytoskeletal 59 kDa antibody; Keratin-10 antibody; Keratin10 antibody; KPP antibody; KRT10 antibody; type I cytoskeletal 10 antibody
Belongs to the intermediate filament family.
Seen in all suprabasal cell layers including stratum corneum. Expressed on the surface of lung cell lines.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.