Lane 1: Anti-Connexin-45 Antibody;
Lane 2: Anti-Connexin-45 Antibody, pre-incubated with the
Rabbit polyclonal primary
Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody (ER1803-93)
Recombinant protein within human connexin 45 aa 257-396 / 396.
SH-SY5Y, A431, rat uterus tissue, human liver cancer tissue, human kidney tissue, human placenta tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
Predicted band size: 45 kDa
Connexin 45 / GJA7 / Cx45
Connexin 45 / GJA7 antibody; Connexin 45 antibody; Connexin-45 antibody; Connexin45 antibody; CX 31.9 antibody; CX 45 antibody; CX31.9 antibody; Cx45 antibody; CXG1_HUMAN antibody; DKFZp686P0738 antibody; Gap junction alpha 7 protein antibody; Gap junction alpha-7 protein antibody; Gap junction gamma 1 protein antibody; Gap junction gamma-1 protein antibody; Gap junction protein alpha 7 45kDa antibody; Gap junction protein alpha 7 antibody; Gap junction protein, gamma 1, 45kDa antibody; GJA 7 antibody; GJA7 antibody; GJC1 antibody; GJD3 antibody
Belongs to the connexin family. Gamma-type subfamily.
Cell membrane, Gap junction.
Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the GJC1 gene. Cx45 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. GJs consist of 3 major connexin (Cx) isoforms—Cx43, Cx40, and Cx45—each of which are characterized by chamber-specific regional distribution and permeation properties. Cx45 is strongly expressed in the early embryonic myocardium and is required for cardiac development (1). Homozygous Cx45-deficient mice are embryonic lethal; however, in the adult heart, Cx45 is expressed mainly at the SA and AV nodes and is not essential for survival of adult mice. Disease-causing mutations in GJ gamma-1 protein (GJC1), which encodes Cx45, have not yet been identified.