PRODUCT CODE: M1004-7

CCDC51 Mouse Monoclonal Antibody [A8-F4-D1] (M1004-7)

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

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+
Western blot analysis of CCDC51 on recombinant protein using anti-CCDC51 antibody at 1/1,000 dilution.
  • Western blot analysis of CCDC51 on recombinant protein using anti-CCDC51 antibody at 1/1,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CCDC51 antibody. Counter stained with hematoxylin
  • Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CCDC51 antibody. Counter stained with hematoxylin.
Western blot analysis of CCDC51 on recombinant protein using anti-CCDC51 antibody at 1/1,000 dilution.

Applications

  • WB

  • IHC-P

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

CCDC51 Mouse Monoclonal Antibody [A8-F4-D1] (M1004-7)

Immunogen

Recombinant protein

Host

Mouse

Positive Control

Recombinant protein, human liver tissue, human lung tissue, human pancreas tissue, human tonsil tissue, human thyroid tissue, human spleen tissue tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A8-F4-D1

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

46 kDa

Isotype

IgG1

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

CCDC51

SYNONYMS

5730568A12Rik antibody; AI551049 antibody; CCD51_HUMAN antibody; CCDC51 antibody; Coiled coil domain containing 51 antibody; Coiled-coil domain-containing protein 51 antibody; FLJ12436 antibody; RGD1311466 antibody

TISSUE SPECIFICITY

Isoform 1: Widely expressed. Isoform 2: Expression is barely detectable.

SUBCELLULAR LOCATION

Membrane, nucleus.

FUNCTION

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.