Auxin response factor Mouse Monoclonal Antibody [14D2] (EM1901-06)

UNIPROT #

J7KE95

PROTEIN NAME

Auxin response factor

SEQUENCE SIMILARITIES

Belongs to the ARF family.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Auxin response factors (ARFs) are transcription factors that bind to auxin response elements in promoters of early auxin response genes and play central roles in many auxin-mediated processes. As transcription factors, ARFs possess a modular structure and consist of three major domains: an amino-terminal DNA-binding domain (DBD); a middle domain, which is responsible for gene activation or repression; and a carboxy-terminal PB1(Phox and Bem1) domain, contained within a region that was previously called domain III/I. ARFs function as transcription activators or repressors, depending on the middle region of the ARF protein; Q-rich middle regions activate transcription, whereas P/S/T-rich middle regions confer repressor activity.