PERP Recombinant Rabbit Monoclonal Antibody [JU04-51]
Catalog# ET7106-59
PERP Recombinant Rabbit Monoclonal Antibody [JU04-51]
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WB
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IHC-P
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Human
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Mouse
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unconjugated
Overview
Product Name
PERP Recombinant Rabbit Monoclonal Antibody [JU04-51]
Antibody Type
Recombinant Rabbit monoclonal Antibody
Immunogen
Synthetic peptide within Human PERP aa 144-193 / 193.
Species Reactivity
Human, Mouse
Validated Applications
WB, IHC-P
Molecular Weight
21 kDa
Positive Control
Human skin tissue, mouse small intestine tissue.
Conjugation
unconjugated
Clone Number
JU04-51
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Protein A affinity purified.
Application Dilution
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WB
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1:500-1:2,000
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IHC-P
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1:50-1:200
Target
Function
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.
Background References
1. Bonkobara M et al. Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes. Br J Dermatol 148:654-664 (2003).
2. Otsuki T et al. Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. DNA Res 12:117-126 (2005).
Sequence Similarity
Belongs to the TMEM47 family.
Tissue Specificity
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.
Subcellular Location
Cell junction. Membrane.
Synonyms
1110017A08Rik an tibody dJ496H19.1 antibody
KCP 1 antibody
KCP-1 antibody
KCP1 antibody
Keratinocyte associated protein 1 antibody
Keratinocyte-associated protein 1 antibody
Keratinocytes associated protein 1 antibody
KRTCAP 1 antibody
KRTCAP1 antibody
p53 apoptosis effector related to PMP 22 antibody
ExpandImages
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Western blot analysis of PERP on human skin tissue lysate using anti-PERP antibody at 1/1,000 dilution.
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Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-PERP antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-PERP antibody. Counter stained with hematoxylin.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"