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FAAH1 Recombinant Rabbit Monoclonal Antibody [JG43-07]

Usd: 385

Specification

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Catalog# ET7109-06

FAAH1 Recombinant Rabbit Monoclonal Antibody [JG43-07]

Application

  • WB

  • IHC-P

Reactivity

  • Human

  • Mouse

Conjugation

  • unconjugated

This product has been cited in peer reviewed publications, see list HERE

Overview

Product Name

FAAH1 Recombinant Rabbit Monoclonal Antibody [JG43-07]

Antibody Type

Recombinant Rabbit monoclonal Antibody

Immunogen

Recombinant protein within Human FAAH1 aa 440-579 / 579.

Species Reactivity

Human, Mouse

Validated Applications

WB, IHC-P

Molecular Weight

63 kDa

Positive Control

SK-Br-3, mouse cerebellum tissue lysate, mouse lung tissue lysate, human prostate cancer tissue, human placenta tissue, mouse testis tissue.

Conjugation

unconjugated

Clone Number

JG43-07

RRID

AB_3070896

Product Features

Form

Liquid

Concentration

Storage Instructions

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Isotype

IgG

Purification Method

Protein A affinity purified.

Application Dilution

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:50-1:200

Target

Function

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.

Background References

1. Wei B Q et al. A second fatty acid amide hydrolase with variable distribution among placental mammals. J Biol Chem 281:36569-36578 (2006).

2. Sipe J C et al. A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Proc Natl Acad Sci USA 99:8394-8399 (2002).

Sequence Similarity

Belongs to the amidase family.

Tissue Specificity

Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate.

Subcellular Location

Cytoskeleton. Endomembrane system.

UNIPROT

SwissProt: O00519 Human

SwissProt: O08914 Mouse

Synonyms

Anandamide amidohydrolase 1 antibody

Anandamide amidohydrolase antibody

FA2H antibody

FAAH antibody

FAAH-1 antibody

FAAH1_HUMAN antibody

Fatty acid 2-hydroxylase antibody

Fatty acid alpha-hydroxylase antibody

Fatty acid amide hydrolase antibody

Fatty-acid amide hydrolase 1 antibody

Expand

Images

  • Western blot analysis of FAAH1 on different lysates using anti-FAAH1 antibody at 1/2,000 dilution.<br /> Positive control:<br /> Lane 1: SK-Br-3 <br /> Lane 2: Mouse cerebellum<br /> Lane 3: Mouse lung<br />

    Western blot analysis of FAAH1 on different lysates using anti-FAAH1 antibody at 1/2,000 dilution.
    Positive control:
    Lane 1: SK-Br-3
    Lane 2: Mouse cerebellum
    Lane 3: Mouse lung

  • Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

    Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-FAAH1 antibody. Counter stained with hematoxylin.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Citation