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LT-alpha Mouse Monoclonal Antibody [C2-F2] (M0807-12)

Price: Regular price $350.00

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Catalog# M0807-12

Mouse Monoclonal to LT-alpha

Tested for

  • WB

Reacts with

  • Human

Specifications

Product Type

Mouse monoclonal primary

Product Name

LT-alpha Mouse Monoclonal Antibody [C2-F2] (M0807-12)

Immunogen

Synthetic peptide within human lt-alpha aa 156-205 / 205.

Host

Mouse

Positive Control

Recombinant LT-alpha(TNF-β)

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

C2-F2

RRID

AB_3072990

APPLICATION DILUTION

  • WB

  • 1:2,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

18 kDa

Isotype

IgG2b

TARGET

UNIPROT #

P01374

PROTEIN NAME

LT-alpha

SYNONYMS

LTalpha antibody;DIF antibody;LT alpha antibody;LT antibody;LT-alpha antibody;Lta antibody;Lymphotoxin alpha (TNF superfamily, member 1) antibody;Lymphotoxin alpha antibody;Lymphotoxin-alpha antibody;TNF B antibody;TNF superfamily member 1 antibody;TNF, lymphocyte-derived antibody;TNF-beta antibody;TNFB antibody;TNFB_HUMAN antibody;TNFbeta antibody;TNFSF1 antibody;TNLG1E antibody;Tumor necrosis factor beta antibody;tumor necrosis factor ligand 1E antibody;Tumor necrosis factor ligand superfamily member 1 antibody

SEQUENCE SIMILARITIES

Belongs to the tumor necrosis factor family.

SUBCELLULAR LOCATION

Secretory

FUNCTION

Lymphotoxin-alpha (LTA), a member of the tumor necrosis factor (TNF) family of cytokines, was initially isolated on the basis of an anti-tumor activity. LTA plays a key role in communication between lymphocytes and stromal cells, thereby eliciting cytotoxic effects on cancer cells. It induces the expression of vascular cell-adhesion molecule 1 (VCAM1) on vascular endothelial cells and recruits natural killer (NK) cells to parenchymal organs and tumor lesions.

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