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Claudin-18.2, AlpHcAbs® Human Alpaca Monoclonal Antibody

Usd: 700

Specification

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Catalog# HA710340

Claudin-18.2, AlpHcAbs® Human Alpaca Monoclonal Antibody

Application

  • ELISA

  • FC

Reactivity

  • Human

Conjugation

  • unconjugated

Overview

Product Name

Claudin-18.2, AlpHcAbs® Human Alpaca Monoclonal Antibody

Antibody Type

Alpaca Nanobody

Immunogen

Recombinant human Claudin-18.2

Product Specificity

Human Claudin-18.2

Species Reactivity

Human

Validated Applications

ELISA, FC

Conjugation

unconjugated

Product Features

Form

Liquid

Concentration

1mg/ml(The concentration of this product may be batch-dependent)

Storage Instructions

Store at –20 ℃, (Avoid freeze / thaw cycles), Stable for 12 months at -20℃

Storage Buffer

Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol

Isotype

VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation)

Purification Method

Immunogen affinity purified.

Application Dilution

  • ELISA

  • 1:4,000-1:10,000

  • FC

  • 1:200-1:1,000

Target

Function

Anti-Claudin-18.2, AlpHcAbs® Human antibody is designed for detecting human Claudin-18.2 specifically. Anti-Claudin-18.2, AlpHcAbs® Human antibody is recombinant VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc. Based on ELISA, Anti-Claudin-18.2, AlpHcAbs® Human antibody reacts with human Claudin-18.2, and has reactivity with cynomolgus Claudin-18.2.

Background References

暂无

Subcellular Location

Cell membrane, tight junction

UNIPROT

SwissProt: P56856-2 Human

Synonyms

Claudin 18 antibody

Claudin-18 antibody

CLD18_HUMAN antibody

CLDN18 antibody

SFTA5 antibody

SFTPJ antibody

Images

  • Advantages of using an Alpaca Recombinant Secondary<br />1. Smaller size<br />Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies.<br />2. Easier to use<br />Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use. <br />3. Easier production<br />When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies. <br />4. More consistent<br />Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift.<br />5. Higher Affinity<br />Nanobodies benefit from consistently high binding affinity values.

    Advantages of using an Alpaca Recombinant Secondary
    1. Smaller size
    Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies.
    2. Easier to use
    Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use.
    3. Easier production
    When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies.
    4. More consistent
    Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift.
    5. Higher Affinity
    Nanobodies benefit from consistently high binding affinity values.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"