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FPR1 Rabbit Polyclonal Antibody

Usd: 315

Specification

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Catalog# R1511-36

FPR1 Rabbit Polyclonal Antibody

Application

  • WB

  • IHC-P

Reactivity

  • Human

  • Mouse

Conjugation

  • unconjugated

This product has been cited in peer reviewed publications, see list HERE

Overview

Product Name

FPR1 Rabbit Polyclonal Antibody

Antibody Type

Rabbit Polyclonal Antibody

Immunogen

Synthetic peptide within Mouse FPR1 aa 151-200 / 364

Species Reactivity

Human, Mouse

Validated Applications

WB, IHC-P

Molecular Weight

38 kDa

Positive Control

NCCIT, MEF, HES, human tonsil tissue, human spleen tissue.

Conjugation

unconjugated

RRID

AB_3073380

Product Features

Form

Liquid

Concentration

Storage Instructions

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Isotype

IgG

Purification Method

Immunogen affinity purified.

Application Dilution

  • WB

  • 1:500

  • IHC-P

  • 1:50-1:100

Target

Function

High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Background References

暂无

Sequence Similarity

Belongs to the G-protein coupled receptor 1 family.

Tissue Specificity

Neutrophils.

Post-translational Modification

Phosphorylated; which is necessary for desensitization.

Subcellular Location

Cell membrane.

UNIPROT

SwissProt: P21462 Human

Synonyms

fMet Leu Phe receptor antibody

fMet-Leu-Phe receptor antibody

FMLP antibody

fMLP receptor antibody

FMLPR antibody

Formyl peptide receptor 1 antibody

FPR 1 antibody

FPR antibody

FPR receptor antibody

FPR1 antibody

Expand

Images

  • Western blot analysis of FPR1 on different cell lysate using anti-FPR1 antibody at 1/500 dilution.<br /><span style="font-weight: bold;">Positive control:</span><br />Lane 1: NCCIT<br />Lane 2: MEF<br />Lane 3: HES

    Western blot analysis of FPR1 on different cell lysate using anti-FPR1 antibody at 1/500 dilution.
    Positive control:
    Lane 1: NCCIT
    Lane 2: MEF
    Lane 3: HES

  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FPR1 antibody. Counter stained with hematoxylin.

    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FPR1 antibody. Counter stained with hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-FPR1 antibody. Counter stained with hematoxylin.

    Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-FPR1 antibody. Counter stained with hematoxylin.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Citation