DARS2 Rabbit Polyclonal Antibody
Catalog# ER1901-77
DARS2 Rabbit Polyclonal Antibody
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IF-Tissue
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Zebrafish
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unconjugated
Overview
Product Name
DARS2 Rabbit Polyclonal Antibody
Antibody Type
Rabbit Polyclonal Antibody
Immunogen
Recombinant protein within zebrafish DARS2 aa 43-321 / 660.
Species Reactivity
Zebrafish
Validated Applications
IF-Tissue
Molecular Weight
Predicted band size: 74 kDa
Positive Control
Zebrafish tissue.
Conjugation
unconjugated
RRID
Product Features
Form
Liquid
Concentration
Storage Instructions
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Isotype
IgG
Purification Method
Immunogen affinity purified.
Application Dilution
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IF-Tissue
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1:50-1:200
Target
Function
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
Background References
1. Reiling E et al. Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. Eur J Hum Genet 17(8):1056-1062 (2009).
Subcellular Location
Mitochondrion.
UNIPROT
Synonyms
Aspartyl-tRNA synthetase 2, mitochondrial
Images
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IF staining of DARS2 in whole Zebrafish tissue (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"