Recombinant protein within Human Annexin A3 aa 2-323.
Species Reactivity
Human, Mouse, Rat
Validated Applications
WB, IHC-P, FC
Target Molecular Weight
Predicted band size: 36 kDa
Positive Control
Siha, Hela, rat spleen tissue lysate, rat liver tissue lysate, mouse lung tissue lysate, rat kidney tissue, human colon cancer tissue, human spleen tissue, human prostate tissue, A431.
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.
Western blot analysis of Annexin A3 on different lysates using anti-Annexin A3 antibody at 1/1,000 dilution. Positive control: Lane 1: Siha Lane 2: Hela Lane 3: Rat spleen tissue Lane 4: Rat liver tissue Lane 5: Mouse lung tissue
Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-Annexin A3 antibody. Counter stained with hematoxylin.
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