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Parvalbumin [JM100-08]

Product code: ET1703-15


  • Overview

  • Product name Parvalbumin
  • Molecular Wt 12 kDa
  • Description Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
  • Species reactivity Human
  • Tested applications WB,IHC,IP
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control Human tonsil tissue.
  • Conjugate Non-conjugated
  • Clone number JM100-08
  • Alternative names D22S749 antibody
    MGC116759 antibody
    Parvalbumin alpha antibody
    PRVA_HUMAN antibody
    PVALB antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cytoplasm, nucleus.
  • Database links P20472(Human)
  • Applications

    WB: 1:500-1:1,000
    IHC: 1:50-1:200

  • Publishing research using Parvalbumin? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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