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Ctip2 [JF09-90]

Product code: ET1702-76

  • Overview

  • Product name Ctip2
  • Molecular Wt 100/110kDa
  • Description Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
  • Species reactivity Human
  • Tested applications WB,ICC,IHC,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control THP-1, LO2, mouse brain tissue.
  • Conjugate Non-conjugated
  • Clone number JF09-90
  • Alternative names ATL1 alpha antibody
    ATL1 antibody
    ATL1 beta antibody
    ATL1 gamma antibody
    ATL1-delta antibody
    B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein antibody
    B cell lymphoma/leukemia 11B antibody
    B-cell CLL/lymphoma 11B (zinc finger protein) antibody
    B-cell CLL/lymphoma 11B antibody
    B-cell lymphoma/leukemia 11B antibody
    BC11B_HUMAN antibody
    BCL-11B antibody
    Bcl11b antibody
    BCL11B/TRDC fusion antibody
    COUP TF interacting protein 2 antibody
    COUP-TF interacting protein 2 antibody
    COUP-TF-interacting protein 2 antibody
    Ctip 2 antibody
    CTIP-2 antibody
    CTIP2 antibody
    hRIT1 alpha antibody
    hRit1 antibody
    Radiation induced tumor suppressor gene 1 antibody
    Radiation induced tumor suppressor gene 1 protein antibody
    Radiation-induced tumor suppressor gene 1 protein antibody
    Rit 1 antibody
    Rit1 antibody
    zinc finger protein hRit1 alpha antibody
    ZNF856B antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Nucleus.
  • Database links Q9C0K0(Human)
  • Applications

    WB: 1:1,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200
    FC: 1:50-1:100

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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