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p38 [JF55-07]

Product code: ET1702-65

  • Overview

  • Product name p38
  • Molecular Wt 41 kDa
  • Description MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,ICC/IF,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control NIH/3T3, 293T, Hela, 293, human brain tissue, mouse heart tissue.
  • Conjugate Non-conjugated
  • Clone number JF55-07
  • Alternative names CSAID-binding protein antibody
    Csaids binding protein antibody
    CSBP antibody
    CSBP1 antibody
    CSBP2 antibody
    CSPB1 antibody
    Cytokine suppressive anti-inflammatory drug-binding protein antibody
    EXIP antibody
    MAP kinase 14 antibody
    MAP kinase MXI2 antibody
    MAP kinase p38 alpha antibody
    MAPK 14 antibody
    MAPK14 antibody
    MAX-interacting protein 2 antibody
    Mitogen-activated protein kinase 14 antibody
    Mitogen-activated protein kinase p38 alpha antibody
    MK14_HUMAN antibody
    Mxi2 antibody
    p38 antibody
    p38 MAP kinase antibody
    p38 mitogen activated protein kinase antibody
    p38ALPHA antibody
    p38alpha Exip antibody
    PRKM14 antibody
    PRKM15 antibody
    RK antibody
    SAPK2A antibody
    Stress-activated protein kinase 2a antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A purified.
  • Subcellular location Cytoplasm, Nucleus.
  • Database links Q16539(Human)
  • Applications

    WB: 1:1,000-1:2,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200

  • Publishing research using p38? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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