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gamma Catenin [JF0973]

Product code: ET1702-33


  • Overview

  • Product name gamma Catenin
  • Molecular Wt 82 kDa
  • Description The catenins, α, β and γ, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP? associates with catenin/cadherin complexes and may regulate complex signaling.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,ICC/IF,IHC,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control A431, MCF-7, Hela, mouse stomach tissue.
  • Conjugate Non-conjugated
  • Clone number JF0973
  • Alternative names ARVD 12 antibody
    ARVD12 antibody
    Catenin (cadherin associated protein), gamma 80kDa antibody
    catenin (cadherin-associated protein) gamma (80kD) antibody
    Catenin gamma antibody
    CTNNG antibody
    Desmoplakin 3 antibody
    Desmoplakin III antibody
    Desmoplakin-3 antibody
    Desmoplakin3 antibody
    DesmoplakinIII antibody
    DP 3 antibody
    DP III antibody
    DP3 antibody
    DPIII antibody
    gamma catenin antibody
    Junction plakoglobin antibody
    JUP antibody
    OTTHUMP00000164732 antibody
    OTTHUMP00000164735 antibody
    OTTHUMP00000164738 antibody
    PDGB antibody
    PKGB antibody
    PLAK_HUMAN antibody
    PLAKOGLOBIN antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cell junction, Cytoplasm, Membrane.
  • Database links P14923(Human)
    Q02257(Mouse)
    Q6P0K8(Rat)
  • Applications

    WB: 1:1,000-1:2,000
    ICC: 1:100-1:500
    IHC: 1:50-1:200
    FC: 1:50-1:100

  • Publishing research using gamma Catenin? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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