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Estrogen Receptor beta [JJ09-02]

Product code: ET1701-69

  • Overview

  • Product name Estrogen Receptor beta
  • Molecular Wt 59 kDa
  • Description Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.
  • Species reactivity Human
  • Tested applications WB
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control 293T, human breast carcinoma tissue.
  • Conjugate Non-conjugated
  • Clone number JJ09-02
  • Alternative names ER BETA antibody
    ER-beta antibody
    Erb antibody
    ESR B antibody
    ESR BETA antibody
    ESR2 antibody
    ESR2_HUMAN antibody
    ESRB antibody
    ESTRB antibody
    estrogen nuclear receptor beta variant a antibody
    estrogen nuclear receptor beta variant b antibody
    estrogen receptor 2 (ER beta) antibody
    Estrogen receptor 2 antibody
    estrogen receptor beta 4 antibody
    Estrogen receptor beta antibody
    NR3A2 antibody
    Nuclear receptor subfamily 3 group A member 2 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Nucleus.
  • Database links Q92731(Human)
  • Applications

    WB: 1:1,000-1:2,000

  • Publishing research using Estrogen Receptor beta? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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