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SOX18 [ST43-02]

Product code: ET1609-11


  • Overview

  • Product name SOX18
  • Molecular Wt 41 kDa
  • Description Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,IHC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen recombinant protein
  • Positive control K562.
  • Conjugate Non-conjugated
  • Clone number ST43-02
  • Alternative names HLTS antibody
    SOX 18 antibody
    Sox18 antibody
    SOX18_HUMAN antibody
    SRY (sex determining region Y) box 18 antibody
    SRY box 18 antibody
    Transcription factor SOX 18 antibody
    Transcription factor SOX-18 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Nucleus.
  • Database links P35713(Human)
    P43680(Mouse)
    EntrezGene:311723(Rat)
  • Applications

    WB: 1:1,000
    IHC:1:50-1:200

  • Publishing research using SOX18? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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