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PDLIM1 [JE55-21]

Product code: ET7110-99


  • Overview

  • Product name PDLIM1
  • Molecular Wt 36 kDa
  • Description PDLIM1, also known as CLP36, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with Actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (a kinase) and recruits Clik1 to α-actinin-1, thereby facilitating the association of Clik1 with Actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88% sequence similarity with its rat counterpart, suggesting a conserved function between species.
  • Species reactivity Human,Mouse,Rat
  • Tested applications WB,IHC-P,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Synthetic peptide within N-terminal Human PDLIM1.
  • Positive control Human placenta tissue lysate, mouse lung tissue lysate, HepG2 cell lysate, rat heart tissue, HepG2.
  • Conjugate Non-conjugated
  • Clone number JE55-21
  • Alternative names C terminal LIM domain protein 1 antibody
    C-terminal LIM domain protein 1 antibody
    Carboxy terminal LIM domain protein 1 antibody
    CLIM 1 antibody
    CLIM1 antibody
    CLP 36 antibody
    CLP36 antibody
    Elfin antibody
    Enigma antibody
    Enigma homolog antibody
    hCLIM 1 antibody
    hCLIM1 antibody
    LIM domain protein CLP 36 antibody
    LIM domain protein CLP-36 antibody
    LIM domain protein CLP36 antibody
    PDLI1_HUMAN antibody
    PDLIM 1 antibody
    Pdlim1 antibody
    PDZ and LIM domain 1 antibody
    PDZ and LIM domain protein 1 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A affinity purified.
  • Subcellular location Cytoskeleton, cytoplasm, Z line.
  • Database links SwissProt: O00151 Human
    SwissProt: O70400 Mouse
    SwissProt: Q3TZ17 Mouse
    SwissProt: P52944 Rat
  • Applications

    WB:1:1,000-1:2,000
    IHC-P:1:50-1:200
    FC:1:50-1:100

  • Publishing research using PDLIM1? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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