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SARS-CoV-2 Nucleocapsid protein

Product code: HAg2002

  • Overview

  • Product name SARS-CoV-2 Nucleocapsid protein
  • Catalog No. HAg2002
  • Endotoxin Not tested.
  • Formulation 1×PBS, pH 7.4
  • Background

  • The nucleocapsid protein (N-protein) is a structural protein that binds to the coronavirus RNA genome, thus creating a shell (or capsid) around the enclosed nucleic acid. The N-protein also interacts with the viral membrane protein during viral assembly, assists in RNA synthesis and folding, plays a role in virus budding, and affects host cell responses, including cell cycle and translation. Coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
  • Product Information

  • Expressed Host BL21
  • Tag N-terminal histidine tag
  • Usage guide

  • Storage Upon arrival, the protein may be stored for 2 weeks at 4 ℃. For long term storage, it is recommended to store at -20 ℃ or -80 ℃ in appropriate aliquots. Avoid repeated freeze-thaw cycles.
  • Reconstitution Full length
  • Publishing research using SARS-CoV-2 Nucleocapsid protein? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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