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SARS-CoV-2 RBD-hFc protein

Product code: HAg2001

  • Overview

  • Product name SARS-CoV-2 RBD-hFc protein
  • Catalog No. HAg2001
  • Bio-Activity Activity
  • Purity >95%
  • Endotoxin Not tested.
  • Formulation 1×PBS, pH 7.4
  • Concentration 1.26 mg/mL
  • Background

  • Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
  • Product Information

  • Expressed Host 293 cell
  • Tag C-terminal hFc tag
  • Usage guide

  • Storage Upon arrival, the protein may be stored for 2 weeks at 4 ℃. For long term storage, it is recommended to store at -20 ℃ or -80 ℃ in appropriate aliquots. Avoid repeated freeze-thaw cycles.
  • Reconstitution aa319-aa541
  • Publishing research using SARS-CoV-2 RBD-hFc protein? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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