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ABAT/GABA-T [JE50-16]

Product code: ET7110-01


  • Overview

  • Product name ABAT/GABA-T
  • Molecular Wt 52 kDa
  • Description 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,IHC,IP
  • Antibody type Recombinant Rabbit monoclonal Antibody
  • Immunogen Synthetic peptide within N-terminal human ABAT/GABA-T.
  • Positive control Human liver tissue, rat liver tissue, human liver cancer tissue, human placenta tissue, mouse kidney tissue.
  • Conjugate Non-conjugated
  • Clone number JE50-16
  • Alternative names (S) 3 amino 2 methylpropionate transaminase antibody
    (S)-3-amino-2-methylpropionate transaminase antibody
    4 aminobutyrate aminotransferase antibody
    4 aminobutyrate aminotransferase, mitochondrial antibody
    4-aminobutyrate aminotransferase antibody
    ABAT antibody
    FLJ17813 antibody
    FLJ30272 antibody
    GABA aminotransferase antibody
    GABA AT antibody
    GABA T antibody
    GABA transaminase antibody
    GABA transferase antibody
    GABA-AT antibody
    GABA-T antibody
    GABAT antibody
    GABT_HUMAN antibody
    Gamma amino N butyrate transaminase antibody
    Gamma-amino-N-butyrate transaminase antibody
    hCG1984265 antibody
    L AIBAT antibody
    L-AIBAT antibody
    LAIBAT antibody
    mitochondrial antibody
    NPD009 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A affinity purified.
  • Subcellular location Mitochondrion.
  • Database links SwissProt:P80404 Human
    SwissProt:P61922 Mouse
    SwissProt:P50554 Rat
  • Applications

    WB:1:500-1:1,000
    IP:1:50
    IHC:1:50-1:200

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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