Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart.
Human, Mouse, Rat, Cow, Sheep
Rabbit Polyclonal Antibody
KLH conjugated synthetic peptide derived from human C6orf25 1-100/241
Expressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets.
Chromosome 6 open reading frame 25
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
affinity purified by Protein A
Isoform E: Endoplasmic reticulum. Golgi apparatus.
Isoform D: Endoplasmic reticulum. Golgi apparatus.
Isoform B: Cell membrane; Single-pass type I membrane protein.
Isoform A: Cell membrane; Single-pass type I membrane protein.
SwissProt: O95866 Human
Fig1: Protein: mouse testis lysate;
Primary: rabbit Anti-C6orf25 (ER1905-08) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 24 kD
Observed band size: 24 kD
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