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Brachyury / Bry [JE44-11]

Product code: ET7109-35

  • Overview

  • Product name Brachyury / Bry
  • Molecular Wt 47 kDa
  • Description The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. Genetic variations in T are associated with susceptibility to neural tube defects (NTD). NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis.
  • Species reactivity Human, Mouse
  • Tested applications WB,IHC,FC,IP
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Recombinant protein within human Brachyury/ Bry aa 200-400.
  • Positive control SH-SY-5Y, Mouse E14.5 embryo tissue.
  • Conjugate Non-conjugated
  • Clone number JE44-11
  • Alternative names BRAC_HUMAN antibody
    Brachyury homolog antibody
    Brachyury protein antibody
    Bry antibody
    MGC104817 antibody
    Protein T antibody
    SAVA antibody
    T antibody
    T brachyury homolog antibody
    T brachyury transcription factor antibody
    T Protein antibody
    T, brachyury homolog (mouse) antibody
    TFT antibody
    Transcription factor T antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/ml.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity Protein A purified.
  • Subcellular location Nucleus.
  • Database links SwissProt: O15178 Human
    SwissProt: P20293 Mouse
  • Applications

    WB: 1:500
    IHC: 1:50-1:200
    FC: 1:50-1:100
    IP: 1:10-1:50

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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