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ILF3 [JG37-63]

Product code: ET7108-49

  • Overview

  • Product name ILF3
  • Molecular Wt 75/95 kDa
  • Description ILF3 (interleukin enhancer binding factor 3) or TCP80 (translational control protein 80), is a ubiquitously expressed nuclear protein that exists in a heterodimer with NF45. NF90 contains two DRBM (double-stranded RNA(dsRNA-)-binding) domains and one DZF domain and, in association with NF45 primarily participates in the regulation of IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES). NF45 and NF90 belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. Due to alternative splicing events, six isoforms exist for NF90, namely NFAR-2 (or ILF3-E), NFAR-1 (or DRBP76), isoform 3, DRBP76α (or ILF3-A), DRBP76δ (also known as DRBP76γ or ILF3-C) and isoform 6.
  • Species reactivity Human, Mouse, Rat
  • Tested applications WB,IP,ICC,IF,IHC,FC
  • Antibody type Recombinant Rabbit Monoclonal Antibody
  • Immunogen Recombinant protein of N-terminal human ILF3.
  • Positive control Rat heart tissue lysate, 293, A431, SH-SY-5Y, SiHa, human tonsil tissue, human colon tissue, human prostate cancer tissue, mouse testis tissue, mouse kidney tissue.
  • Conjugate Non-conjugated
  • Clone number JG37-63
  • Alternative names CBTF antibody
    Double stranded RNA binding protein 76 antibody
    Double-stranded RNA-binding protein 76 antibody
    DRBF antibody
    DRBP76 antibody
    ILF3 antibody
    ILF3_HUMAN antibody
    Interleukin enhancer binding factor 3 antibody
    Interleukin enhancer-binding factor 3 antibody
    M phase phosphoprotein 4 antibody
    M-phase phosphoprotein 4 antibody
    MPHOSPH4 antibody
    MPP4 antibody
    NF AT 90 antibody
    NF-AT-90 antibody
    NF110 antibody
    NF90 antibody
    NFAR antibody
    Nuclear factor associated with dsRNA antibody
    Nuclear factor of activated T cells 90 kDa antibody
    Nuclear factor of activated T-cells 90 kDa antibody
    TCP80 antibody
    Translational control protein 80 antibody
  • Properties

  • Form Liquid
  • Concentration 1 mg/mL.
  • Storage instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • Buffer 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • Isotype IgG
  • Purity ProA affinity purified
  • Subcellular location Cytoplasm. Nucleus.
  • Database links Q12906(Human)
  • Applications

    WB: 1:500-1:2,000
    ICC: 1:50-1:200
    IHC: 1:50-1:200
    FC: 1:50-1:100
    IP: 1:10-1:50

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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